LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Nintedanib | 3.33 | uM | LJP6 | 1 | H02 | 72 | hr | 1235 | 1308 | 4156 | 0.3147 | 0.0249 |
| MCF7 | Nintedanib | 3.33 | uM | LJP6 | 2 | H02 | 72 | hr | 1235 | 1480 | 4156 | 0.3561 | 0.0838 |
| MCF7 | Nintedanib | 3.33 | uM | LJP6 | 3 | H02 | 72 | hr | 1235 | 1602 | 4156 | 0.3855 | 0.1255 |
| MCF7 | NU7441 | 3.33 | uM | LJP5 | 1 | C08 | 72 | hr | 1235 | 3288 | 4156 | 0.7911 | 0.7028 |
| MCF7 | NU7441 | 3.33 | uM | LJP5 | 2 | C08 | 72 | hr | 1235 | 3230 | 4156 | 0.7772 | 0.6829 |
| MCF7 | NU7441 | 3.33 | uM | LJP5 | 3 | C08 | 72 | hr | 1235 | 3018 | 4156 | 0.7262 | 0.6103 |
| MCF7 | Dactolisib | 3.33 | uM | LJP5 | 1 | M14 | 72 | hr | 1235 | 1032 | 4156 | 0.2483 | -0.0696 |
| MCF7 | Dactolisib | 3.33 | uM | LJP5 | 2 | M14 | 72 | hr | 1235 | 1278 | 4156 | 0.3075 | 0.0146 |
| MCF7 | Dactolisib | 3.33 | uM | LJP5 | 3 | M14 | 72 | hr | 1235 | 1310 | 4156 | 0.3152 | 0.0255 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 1 | K14 | 72 | hr | 1235 | 949 | 4156 | 0.2283 | -0.0981 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 2 | K14 | 72 | hr | 1235 | 1032 | 4156 | 0.2483 | -0.0696 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 3 | K14 | 72 | hr | 1235 | 1082 | 4156 | 0.2603 | -0.0525 |
| MCF7 | Palbociclib | 3.33 | uM | LJP6 | 1 | E14 | 72 | hr | 1235 | 1888 | 4156 | 0.4543 | 0.2234 |
| MCF7 | Palbociclib | 3.33 | uM | LJP6 | 2 | E14 | 72 | hr | 1235 | 2024 | 4156 | 0.4870 | 0.2700 |
| MCF7 | Palbociclib | 3.33 | uM | LJP6 | 3 | E14 | 72 | hr | 1235 | 1887 | 4156 | 0.4540 | 0.2231 |
| MCF7 | PD0325901 | 3.33 | uM | LJP5 | 1 | C02 | 72 | hr | 1235 | 1689 | 4156 | 0.4064 | 0.1553 |
| MCF7 | PD0325901 | 3.33 | uM | LJP5 | 2 | C02 | 72 | hr | 1235 | 1816 | 4156 | 0.4369 | 0.1988 |
| MCF7 | PD0325901 | 3.33 | uM | LJP5 | 3 | C02 | 72 | hr | 1235 | 1623 | 4156 | 0.3905 | 0.1327 |
| MCF7 | PD0325901 | 3.33 | uM | LJP6 | 1 | E02 | 72 | hr | 1235 | 1569 | 4156 | 0.3775 | 0.1142 |
| MCF7 | PD0325901 | 3.33 | uM | LJP6 | 2 | E02 | 72 | hr | 1235 | 1551 | 4156 | 0.3732 | 0.1081 |
| MCF7 | PD0325901 | 3.33 | uM | LJP6 | 3 | E02 | 72 | hr | 1235 | 1659 | 4156 | 0.3992 | 0.1450 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 1 | I08 | 72 | hr | 1235 | 4800 | 4156 | 1.1549 | 1.2204 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 2 | I08 | 72 | hr | 1235 | 4722 | 4156 | 1.1361 | 1.1937 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 3 | I08 | 72 | hr | 1235 | 5000 | 4156 | 1.2030 | 1.2889 |
| MCF7 | PD184352 | 3.33 | uM | LJP5 | 1 | L08 | 72 | hr | 1235 | 2846 | 4156 | 0.6848 | 0.5514 |