LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PD184352 | 3.33 | uM | LJP5 | 2 | L08 | 72 | hr | 1235 | 2885 | 4156 | 0.6942 | 0.5648 |
| MCF7 | PD184352 | 3.33 | uM | LJP5 | 3 | L08 | 72 | hr | 1235 | 2960 | 4156 | 0.7122 | 0.5905 |
| MCF7 | Pelitinib | 3.33 | uM | LJP5 | 1 | I14 | 72 | hr | 1235 | 1852 | 4156 | 0.4456 | 0.2111 |
| MCF7 | Pelitinib | 3.33 | uM | LJP5 | 2 | I14 | 72 | hr | 1235 | 2022 | 4156 | 0.4865 | 0.2693 |
| MCF7 | Pelitinib | 3.33 | uM | LJP5 | 3 | I14 | 72 | hr | 1235 | 1940 | 4156 | 0.4668 | 0.2412 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 1 | E08 | 72 | hr | 1235 | 1251 | 4156 | 0.3010 | 0.0053 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 2 | E08 | 72 | hr | 1235 | 1159 | 4156 | 0.2789 | -0.0262 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 3 | E08 | 72 | hr | 1235 | 1235 | 4156 | 0.2972 | -0.0001 |
| MCF7 | PF477736 | 3.33 | uM | LJP5 | 1 | J20 | 72 | hr | 1235 | 1584 | 4156 | 0.3811 | 0.1194 |
| MCF7 | PF477736 | 3.33 | uM | LJP5 | 2 | J20 | 72 | hr | 1235 | 1700 | 4156 | 0.4090 | 0.1591 |
| MCF7 | PF477736 | 3.33 | uM | LJP5 | 3 | J20 | 72 | hr | 1235 | 1738 | 4156 | 0.4182 | 0.1721 |
| MCF7 | PF562271 | 3.33 | uM | LJP6 | 1 | F14 | 72 | hr | 1235 | 964 | 4156 | 0.2319 | -0.0929 |
| MCF7 | PF562271 | 3.33 | uM | LJP6 | 2 | F14 | 72 | hr | 1235 | 956 | 4156 | 0.2300 | -0.0957 |
| MCF7 | PF562271 | 3.33 | uM | LJP6 | 3 | F14 | 72 | hr | 1235 | 1038 | 4156 | 0.2498 | -0.0676 |
| MCF7 | PHA-665752 | 3.33 | uM | LJP5 | 1 | F14 | 72 | hr | 1235 | 3555 | 4156 | 0.8554 | 0.7942 |
| MCF7 | PHA-665752 | 3.33 | uM | LJP5 | 2 | F14 | 72 | hr | 1235 | 3834 | 4156 | 0.9225 | 0.8897 |
| MCF7 | PHA-665752 | 3.33 | uM | LJP5 | 3 | F14 | 72 | hr | 1235 | 3901 | 4156 | 0.9386 | 0.9126 |
| MCF7 | PHA-793887 | 3.33 | uM | LJP6 | 1 | E20 | 72 | hr | 1235 | 985 | 4156 | 0.2370 | -0.0857 |
| MCF7 | PHA-793887 | 3.33 | uM | LJP6 | 2 | E20 | 72 | hr | 1235 | 1183 | 4156 | 0.2846 | -0.0179 |
| MCF7 | PHA-793887 | 3.33 | uM | LJP6 | 3 | E20 | 72 | hr | 1235 | 1262 | 4156 | 0.3037 | 0.0091 |
| MCF7 | PI103 | 3.33 | uM | LJP6 | 1 | I14 | 72 | hr | 1235 | 1086 | 4156 | 0.2613 | -0.0511 |
| MCF7 | PI103 | 3.33 | uM | LJP6 | 2 | I14 | 72 | hr | 1235 | 1215 | 4156 | 0.2923 | -0.0070 |
| MCF7 | PI103 | 3.33 | uM | LJP6 | 3 | I14 | 72 | hr | 1235 | 1143 | 4156 | 0.2750 | -0.0316 |
| MCF7 | PLX-4720 | 3.33 | uM | LJP5 | 1 | K02 | 72 | hr | 1235 | 3228 | 4156 | 0.7767 | 0.6822 |
| MCF7 | PLX-4720 | 3.33 | uM | LJP5 | 2 | K02 | 72 | hr | 1235 | 3248 | 4156 | 0.7815 | 0.6891 |