LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | WZ3105 | 1.11 | uM | LJP5 | 1 | D21 | 72 | hr | 1235 | 805 | 4156 | 0.1937 | -0.1474 |
| MCF7 | WZ3105 | 1.11 | uM | LJP5 | 2 | D21 | 72 | hr | 1235 | 942 | 4156 | 0.2267 | -0.1005 |
| MCF7 | WZ3105 | 1.11 | uM | LJP5 | 3 | D21 | 72 | hr | 1235 | 966 | 4156 | 0.2324 | -0.0922 |
| MCF7 | XMD11-50 | 1.11 | uM | LJP6 | 1 | P09 | 72 | hr | 1235 | 2061 | 4156 | 0.4959 | 0.2827 |
| MCF7 | XMD11-50 | 1.11 | uM | LJP6 | 2 | P09 | 72 | hr | 1235 | 1954 | 4156 | 0.4701 | 0.2460 |
| MCF7 | XMD11-50 | 1.11 | uM | LJP6 | 3 | P09 | 72 | hr | 1235 | 2075 | 4156 | 0.4993 | 0.2875 |
| MCF7 | Y39983 | 1.11 | uM | LJP6 | 1 | P03 | 72 | hr | 1235 | 3396 | 4156 | 0.8171 | 0.7397 |
| MCF7 | Y39983 | 1.11 | uM | LJP6 | 2 | P03 | 72 | hr | 1235 | 3353 | 4156 | 0.8068 | 0.7250 |
| MCF7 | Y39983 | 1.11 | uM | LJP6 | 3 | P03 | 72 | hr | 1235 | 3267 | 4156 | 0.7861 | 0.6956 |
| MCF7 | YM 201636 | 1.11 | uM | LJP5 | 1 | N09 | 72 | hr | 1235 | 2827 | 4156 | 0.6802 | 0.5449 |
| MCF7 | YM 201636 | 1.11 | uM | LJP5 | 2 | N09 | 72 | hr | 1235 | 2965 | 4156 | 0.7134 | 0.5922 |
| MCF7 | YM 201636 | 1.11 | uM | LJP5 | 3 | N09 | 72 | hr | 1235 | 3047 | 4156 | 0.7331 | 0.6203 |
| MCF7 | ZSTK474 | 1.11 | uM | LJP6 | 1 | M15 | 72 | hr | 1235 | 1385 | 4156 | 0.3332 | 0.0512 |
| MCF7 | ZSTK474 | 1.11 | uM | LJP6 | 2 | M15 | 72 | hr | 1235 | 1306 | 4156 | 0.3142 | 0.0242 |
| MCF7 | ZSTK474 | 1.11 | uM | LJP6 | 3 | M15 | 72 | hr | 1235 | 1322 | 4156 | 0.3181 | 0.0297 |
| MCF7 | Afatinib | 3.33 | uM | LJP6 | 1 | G20 | 72 | hr | 1235 | 2215 | 4156 | 0.5329 | 0.3354 |
| MCF7 | Afatinib | 3.33 | uM | LJP6 | 2 | G20 | 72 | hr | 1235 | 2392 | 4156 | 0.5755 | 0.3960 |
| MCF7 | Afatinib | 3.33 | uM | LJP6 | 3 | G20 | 72 | hr | 1235 | 2244 | 4156 | 0.5399 | 0.3453 |
| MCF7 | Sigma A6730 | 3.33 | uM | LJP5 | 1 | B20 | 72 | hr | 1235 | 2263 | 4156 | 0.5445 | 0.3518 |
| MCF7 | Sigma A6730 | 3.33 | uM | LJP5 | 2 | B20 | 72 | hr | 1235 | 2345 | 4156 | 0.5642 | 0.3799 |
| MCF7 | Sigma A6730 | 3.33 | uM | LJP5 | 3 | B20 | 72 | hr | 1235 | 2511 | 4156 | 0.6042 | 0.4367 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 1 | A14 | 72 | hr | 1235 | 563 | 4156 | 0.1355 | -0.2302 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 2 | A14 | 72 | hr | 1235 | 559 | 4156 | 0.1345 | -0.2316 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 3 | A14 | 72 | hr | 1235 | 505 | 4156 | 0.1215 | -0.2501 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 1235 | 881 | 4156 | 0.2120 | -0.1213 |