LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Torin1 | 1.11 | uM | LJP6 | 3 | O15 | 72 | hr | 1235 | 1180 | 4156 | 0.2839 | -0.0190 |
| MCF7 | Torin2 | 1.11 | uM | LJP5 | 1 | I21 | 72 | hr | 1235 | 1129 | 4156 | 0.2716 | -0.0364 |
| MCF7 | Torin2 | 1.11 | uM | LJP5 | 2 | I21 | 72 | hr | 1235 | 1126 | 4156 | 0.2709 | -0.0375 |
| MCF7 | Torin2 | 1.11 | uM | LJP5 | 3 | I21 | 72 | hr | 1235 | 1176 | 4156 | 0.2830 | -0.0203 |
| MCF7 | Tozasertib | 1.11 | uM | LJP5 | 1 | B15 | 72 | hr | 1235 | 1364 | 4156 | 0.3282 | 0.0440 |
| MCF7 | Tozasertib | 1.11 | uM | LJP5 | 2 | B15 | 72 | hr | 1235 | 1392 | 4156 | 0.3349 | 0.0536 |
| MCF7 | Tozasertib | 1.11 | uM | LJP5 | 3 | B15 | 72 | hr | 1235 | 1348 | 4156 | 0.3243 | 0.0386 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 1 | P21 | 72 | hr | 1235 | 2288 | 4156 | 0.5505 | 0.3604 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 2 | P21 | 72 | hr | 1235 | 2152 | 4156 | 0.5178 | 0.3138 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 3 | P21 | 72 | hr | 1235 | 2419 | 4156 | 0.5820 | 0.4052 |
| MCF7 | TWS119 | 1.11 | uM | LJP5 | 1 | M03 | 72 | hr | 1235 | 3820 | 4156 | 0.9191 | 0.8849 |
| MCF7 | TWS119 | 1.11 | uM | LJP5 | 2 | M03 | 72 | hr | 1235 | 4252 | 4156 | 1.0231 | 1.0328 |
| MCF7 | TWS119 | 1.11 | uM | LJP5 | 3 | M03 | 72 | hr | 1235 | 3550 | 4156 | 0.8542 | 0.7925 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 1 | C15 | 72 | hr | 1235 | 4237 | 4156 | 1.0194 | 1.0277 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 2 | C15 | 72 | hr | 1235 | 4184 | 4156 | 1.0067 | 1.0095 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 3 | C15 | 72 | hr | 1235 | 3982 | 4156 | 0.9581 | 0.9404 |
| MCF7 | Withaferin A | 1.11 | uM | LJP5 | 1 | G15 | 72 | hr | 1235 | 1587 | 4156 | 0.3818 | 0.1204 |
| MCF7 | Withaferin A | 1.11 | uM | LJP5 | 2 | G15 | 72 | hr | 1235 | 1549 | 4156 | 0.3727 | 0.1074 |
| MCF7 | Withaferin A | 1.11 | uM | LJP5 | 3 | G15 | 72 | hr | 1235 | 1553 | 4156 | 0.3737 | 0.1087 |
| MCF7 | Withaferin A | 1.11 | uM | LJP6 | 1 | G15 | 72 | hr | 1235 | 1279 | 4156 | 0.3077 | 0.0149 |
| MCF7 | Withaferin A | 1.11 | uM | LJP6 | 2 | G15 | 72 | hr | 1235 | 1414 | 4156 | 0.3402 | 0.0612 |
| MCF7 | Withaferin A | 1.11 | uM | LJP6 | 3 | G15 | 72 | hr | 1235 | 1320 | 4156 | 0.3176 | 0.0290 |
| MCF7 | WYE-125132 | 1.11 | uM | LJP6 | 1 | L09 | 72 | hr | 1235 | 1789 | 4156 | 0.4304 | 0.1895 |
| MCF7 | WYE-125132 | 1.11 | uM | LJP6 | 2 | L09 | 72 | hr | 1235 | 1604 | 4156 | 0.3859 | 0.1262 |
| MCF7 | WYE-125132 | 1.11 | uM | LJP6 | 3 | L09 | 72 | hr | 1235 | 1950 | 4156 | 0.4692 | 0.2447 |