LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Alpelisib | 1.11 | uM | LJP5 | 2 | N03 | 72 | hr | 1235 | 2393 | 4156 | 0.5758 | 0.3963 |
| MCF7 | Alpelisib | 1.11 | uM | LJP5 | 3 | N03 | 72 | hr | 1235 | 2185 | 4156 | 0.5257 | 0.3251 |
| MCF7 | Luminespib | 1.11 | uM | LJP5 | 1 | H15 | 72 | hr | 1235 | 1435 | 4156 | 0.3453 | 0.0683 |
| MCF7 | Luminespib | 1.11 | uM | LJP5 | 2 | H15 | 72 | hr | 1235 | 1492 | 4156 | 0.3590 | 0.0879 |
| MCF7 | Luminespib | 1.11 | uM | LJP5 | 3 | H15 | 72 | hr | 1235 | 1517 | 4156 | 0.3650 | 0.0964 |
| MCF7 | A443654 | 1.11 | uM | LJP6 | 1 | I21 | 72 | hr | 1235 | 774 | 4156 | 0.1862 | -0.1580 |
| MCF7 | A443654 | 1.11 | uM | LJP6 | 2 | I21 | 72 | hr | 1235 | 785 | 4156 | 0.1889 | -0.1542 |
| MCF7 | A443654 | 1.11 | uM | LJP6 | 3 | I21 | 72 | hr | 1235 | 811 | 4156 | 0.1951 | -0.1453 |
| MCF7 | OSI-027 | 1.11 | uM | LJP6 | 1 | E09 | 72 | hr | 1235 | 2112 | 4156 | 0.5082 | 0.3001 |
| MCF7 | OSI-027 | 1.11 | uM | LJP6 | 2 | E09 | 72 | hr | 1235 | 1817 | 4156 | 0.4372 | 0.1991 |
| MCF7 | OSI-027 | 1.11 | uM | LJP6 | 3 | E09 | 72 | hr | 1235 | 1993 | 4156 | 0.4795 | 0.2594 |
| MCF7 | XMD11-85h | 1.11 | uM | LJP6 | 1 | P21 | 72 | hr | 1235 | 3479 | 4156 | 0.8371 | 0.7682 |
| MCF7 | XMD11-85h | 1.11 | uM | LJP6 | 2 | P21 | 72 | hr | 1235 | 3108 | 4156 | 0.7478 | 0.6411 |
| MCF7 | XMD11-85h | 1.11 | uM | LJP6 | 3 | P21 | 72 | hr | 1235 | 3730 | 4156 | 0.8975 | 0.8541 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 1 | M03 | 72 | hr | 1235 | 3663 | 4156 | 0.8813 | 0.8312 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 2 | M03 | 72 | hr | 1235 | 3376 | 4156 | 0.8123 | 0.7329 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 3 | M03 | 72 | hr | 1235 | 3259 | 4156 | 0.7841 | 0.6928 |
| MCF7 | WH-4-025 | 1.11 | uM | LJP5 | 1 | O09 | 72 | hr | 1235 | 1014 | 4156 | 0.2440 | -0.0758 |
| MCF7 | WH-4-025 | 1.11 | uM | LJP5 | 2 | O09 | 72 | hr | 1235 | 1285 | 4156 | 0.3092 | 0.0170 |
| MCF7 | WH-4-025 | 1.11 | uM | LJP5 | 3 | O09 | 72 | hr | 1235 | 1379 | 4156 | 0.3318 | 0.0492 |
| MCF7 | WZ-4-145 | 1.11 | uM | LJP6 | 1 | J21 | 72 | hr | 1235 | 2079 | 4156 | 0.5002 | 0.2888 |
| MCF7 | WZ-4-145 | 1.11 | uM | LJP6 | 2 | J21 | 72 | hr | 1235 | 2129 | 4156 | 0.5123 | 0.3060 |
| MCF7 | WZ-4-145 | 1.11 | uM | LJP6 | 3 | J21 | 72 | hr | 1235 | 2075 | 4156 | 0.4993 | 0.2875 |
| MCF7 | XMD16-144 | 1.11 | uM | LJP5 | 1 | M09 | 72 | hr | 1235 | 1754 | 4156 | 0.4220 | 0.1776 |
| MCF7 | XMD16-144 | 1.11 | uM | LJP5 | 2 | M09 | 72 | hr | 1235 | 1849 | 4156 | 0.4449 | 0.2101 |