LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | XL147 | 1.11 | uM | LJP5 | 2 | G09 | 72 | hr | 1235 | 4499 | 4156 | 1.0825 | 1.1174 |
| MCF7 | XL147 | 1.11 | uM | LJP5 | 3 | G09 | 72 | hr | 1235 | 3818 | 4156 | 0.9186 | 0.8842 |
| MCF7 | Saracatinib | 1.11 | uM | LJP6 | 1 | D09 | 72 | hr | 1235 | 1555 | 4156 | 0.3741 | 0.1094 |
| MCF7 | Saracatinib | 1.11 | uM | LJP6 | 2 | D09 | 72 | hr | 1235 | 1917 | 4156 | 0.4612 | 0.2334 |
| MCF7 | Saracatinib | 1.11 | uM | LJP6 | 3 | D09 | 72 | hr | 1235 | 1592 | 4156 | 0.3831 | 0.1221 |
| MCF7 | Selumetinib | 1.11 | uM | LJP6 | 1 | M09 | 72 | hr | 1235 | 3115 | 4156 | 0.7495 | 0.6435 |
| MCF7 | Selumetinib | 1.11 | uM | LJP6 | 2 | M09 | 72 | hr | 1235 | 2443 | 4156 | 0.5878 | 0.4135 |
| MCF7 | Selumetinib | 1.11 | uM | LJP6 | 3 | M09 | 72 | hr | 1235 | 2942 | 4156 | 0.7079 | 0.5843 |
| MCF7 | Sirolimus | 1.11 | uM | LJP6 | 1 | L15 | 72 | hr | 1235 | 2576 | 4156 | 0.6198 | 0.4590 |
| MCF7 | Sirolimus | 1.11 | uM | LJP6 | 2 | L15 | 72 | hr | 1235 | 2587 | 4156 | 0.6225 | 0.4628 |
| MCF7 | Sirolimus | 1.11 | uM | LJP6 | 3 | L15 | 72 | hr | 1235 | 2788 | 4156 | 0.6708 | 0.5316 |
| MCF7 | Sorafenib | 1.11 | uM | LJP6 | 1 | B09 | 72 | hr | 1235 | 3864 | 4156 | 0.9297 | 0.9000 |
| MCF7 | Sorafenib | 1.11 | uM | LJP6 | 2 | B09 | 72 | hr | 1235 | 3416 | 4156 | 0.8219 | 0.7466 |
| MCF7 | Sorafenib | 1.11 | uM | LJP6 | 3 | B09 | 72 | hr | 1235 | 3760 | 4156 | 0.9047 | 0.8644 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 1 | J09 | 72 | hr | 1235 | 3773 | 4156 | 0.9078 | 0.8688 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 2 | J09 | 72 | hr | 1235 | 3954 | 4156 | 0.9514 | 0.9308 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 3 | J09 | 72 | hr | 1235 | 3963 | 4156 | 0.9535 | 0.9339 |
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 1 | L03 | 72 | hr | 1235 | 2418 | 4156 | 0.5818 | 0.4049 |
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 2 | L03 | 72 | hr | 1235 | 2675 | 4156 | 0.6436 | 0.4929 |
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 3 | L03 | 72 | hr | 1235 | 2236 | 4156 | 0.5380 | 0.3426 |
| MCF7 | TGX221 | 1.11 | uM | LJP5 | 1 | H21 | 72 | hr | 1235 | 3831 | 4156 | 0.9218 | 0.8887 |
| MCF7 | TGX221 | 1.11 | uM | LJP5 | 2 | H21 | 72 | hr | 1235 | 4111 | 4156 | 0.9891 | 0.9845 |
| MCF7 | TGX221 | 1.11 | uM | LJP5 | 3 | H21 | 72 | hr | 1235 | 4597 | 4156 | 1.1061 | 1.1509 |
| MCF7 | Torin1 | 1.11 | uM | LJP6 | 1 | O15 | 72 | hr | 1235 | 1215 | 4156 | 0.2923 | -0.0070 |
| MCF7 | Torin1 | 1.11 | uM | LJP6 | 2 | O15 | 72 | hr | 1235 | 1161 | 4156 | 0.2793 | -0.0255 |