LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 CGP60474
0.37
uM
LJP6
 2
G04
 72
hr
 1235 667 4156 0.1605 -0.1946
MCF7 CGP60474
0.37
uM
LJP6
 3
G04
 72
hr
 1235 564 4156 0.1357 -0.2299
MCF7 CHIR-99021
0.37
uM
LJP6
 1
P16
 72
hr
 1235 3187 4156 0.7668 0.6682
MCF7 CHIR-99021
0.37
uM
LJP6
 2
P16
 72
hr
 1235 3205 4156 0.7711 0.6744
MCF7 CHIR-99021
0.37
uM
LJP6
 3
P16
 72
hr
 1235 3301 4156 0.7942 0.7072
MCF7 CP724714
0.37
uM
LJP5
 1
A10
 72
hr
 1235 3413 4156 0.8212 0.7456
MCF7 CP724714
0.37
uM
LJP5
 2
A10
 72
hr
 1235 3323 4156 0.7995 0.7148
MCF7 CP724714
0.37
uM
LJP5
 3
A10
 72
hr
 1235 3494 4156 0.8407 0.7733
MCF7 CP466722
0.37
uM
LJP5
 1
I10
 72
hr
 1235 4429 4156 1.0656 1.0934
MCF7 CP466722
0.37
uM
LJP5
 2
I10
 72
hr
 1235 5225 4156 1.2572 1.3659
MCF7 CP466722
0.37
uM
LJP5
 3
I10
 72
hr
 1235 4833 4156 1.1629 1.2317
MCF7 Crizotinib
0.37
uM
LJP5
 1
A22
 72
hr
 1235 2423 4156 0.5830 0.4066
MCF7 Crizotinib
0.37
uM
LJP5
 2
A22
 72
hr
 1235 2579 4156 0.6205 0.4600
MCF7 Crizotinib
0.37
uM
LJP5
 3
A22
 72
hr
 1235 2453 4156 0.5902 0.4169
MCF7 Momelotinib
0.37
uM
LJP5
 1
P10
 72
hr
 1235 3365 4156 0.8096 0.7291
MCF7 Momelotinib
0.37
uM
LJP5
 2
P10
 72
hr
 1235 3312 4156 0.7969 0.7110
MCF7 Momelotinib
0.37
uM
LJP5
 3
P10
 72
hr
 1235 3216 4156 0.7738 0.6781
MCF7 Dasatinib
0.37
uM
LJP5
 1
D04
 72
hr
 1235 931 4156 0.2240 -0.1042
MCF7 Dasatinib
0.37
uM
LJP5
 2
D04
 72
hr
 1235 913 4156 0.2197 -0.1104
MCF7 Dasatinib
0.37
uM
LJP5
 3
D04
 72
hr
 1235 876 4156 0.2108 -0.1230
MCF7 Dasatinib
0.37
uM
LJP6
 1
I04
 72
hr
 1235 922 4156 0.2218 -0.1073
MCF7 Dasatinib
0.37
uM
LJP6
 2
I04
 72
hr
 1235 994 4156 0.2392 -0.0826
MCF7 Dasatinib
0.37
uM
LJP6
 3
I04
 72
hr
 1235 1000 4156 0.2406 -0.0806
MCF7 Dovitinib
0.37
uM
LJP5
 1
E22
 72
hr
 1235 2861 4156 0.6884 0.5566
MCF7 Dovitinib
0.37
uM
LJP5
 2
E22
 72
hr
 1235 3076 4156 0.7401 0.6302