LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 1 | C23 | 72 | hr | 1235 | 1330 | 4156 | 0.3200 | 0.0324 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 2 | C23 | 72 | hr | 1235 | 1244 | 4156 | 0.2993 | 0.0029 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 3 | C23 | 72 | hr | 1235 | 1372 | 4156 | 0.3301 | 0.0468 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 1 | C23 | 72 | hr | 1235 | 1133 | 4156 | 0.2726 | -0.0351 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 2 | C23 | 72 | hr | 1235 | 1121 | 4156 | 0.2697 | -0.0392 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 3 | C23 | 72 | hr | 1235 | 1215 | 4156 | 0.2923 | -0.0070 |
| MCF7 | MK2206 | 0.12 | uM | LJP6 | 1 | F05 | 72 | hr | 1235 | 2249 | 4156 | 0.5411 | 0.3470 |
| MCF7 | MK2206 | 0.12 | uM | LJP6 | 2 | F05 | 72 | hr | 1235 | 2435 | 4156 | 0.5859 | 0.4107 |
| MCF7 | MK2206 | 0.12 | uM | LJP6 | 3 | F05 | 72 | hr | 1235 | 2502 | 4156 | 0.6020 | 0.4337 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 1 | A17 | 72 | hr | 1235 | 2692 | 4156 | 0.6477 | 0.4987 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 2 | A17 | 72 | hr | 1235 | 2993 | 4156 | 0.7201 | 0.6018 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 3 | A17 | 72 | hr | 1235 | 2807 | 4156 | 0.6754 | 0.5381 |
| MCF7 | Nilotinib | 0.12 | uM | LJP5 | 1 | N17 | 72 | hr | 1235 | 4322 | 4156 | 1.0399 | 1.0568 |
| MCF7 | Nilotinib | 0.12 | uM | LJP5 | 2 | N17 | 72 | hr | 1235 | 4417 | 4156 | 1.0628 | 1.0893 |
| MCF7 | Nilotinib | 0.12 | uM | LJP5 | 3 | N17 | 72 | hr | 1235 | 4583 | 4156 | 1.1027 | 1.1461 |
| MCF7 | Nintedanib | 0.12 | uM | LJP6 | 1 | H05 | 72 | hr | 1235 | 3230 | 4156 | 0.7772 | 0.6829 |
| MCF7 | Nintedanib | 0.12 | uM | LJP6 | 2 | H05 | 72 | hr | 1235 | 3688 | 4156 | 0.8874 | 0.8397 |
| MCF7 | Nintedanib | 0.12 | uM | LJP6 | 3 | H05 | 72 | hr | 1235 | 3645 | 4156 | 0.8770 | 0.8250 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 1 | C11 | 72 | hr | 1235 | 4399 | 4156 | 1.0584 | 1.0831 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 2 | C11 | 72 | hr | 1235 | 4195 | 4156 | 1.0093 | 1.0133 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 3 | C11 | 72 | hr | 1235 | 3888 | 4156 | 0.9355 | 0.9082 |
| MCF7 | Dactolisib | 0.12 | uM | LJP5 | 1 | M17 | 72 | hr | 1235 | 1689 | 4156 | 0.4064 | 0.1553 |
| MCF7 | Dactolisib | 0.12 | uM | LJP5 | 2 | M17 | 72 | hr | 1235 | 1834 | 4156 | 0.4413 | 0.2050 |
| MCF7 | Dactolisib | 0.12 | uM | LJP5 | 3 | M17 | 72 | hr | 1235 | 1810 | 4156 | 0.4355 | 0.1967 |
| MCF7 | NVP-TAE684 | 0.12 | uM | LJP6 | 1 | K17 | 72 | hr | 1235 | 1452 | 4156 | 0.3494 | 0.0742 |