LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 WZ-4-145
0.37
uM
LJP6
 1
J22
 72
hr
 1235 2458 4156 0.5914 0.4186
MCF7 WZ-4-145
0.37
uM
LJP6
 2
J22
 72
hr
 1235 2648 4156 0.6371 0.4836
MCF7 WZ-4-145
0.37
uM
LJP6
 3
J22
 72
hr
 1235 2373 4156 0.5710 0.3895
MCF7 XMD16-144
0.37
uM
LJP5
 1
M10
 72
hr
 1235 1776 4156 0.4273 0.1851
MCF7 XMD16-144
0.37
uM
LJP5
 2
M10
 72
hr
 1235 1754 4156 0.4220 0.1776
MCF7 XMD16-144
0.37
uM
LJP5
 3
M10
 72
hr
 1235 1835 4156 0.4415 0.2053
MCF7 Brivanib
0.37
uM
LJP5
 1
P16
 72
hr
 1235 3588 4156 0.8633 0.8055
MCF7 Brivanib
0.37
uM
LJP5
 2
P16
 72
hr
 1235 3663 4156 0.8813 0.8312
MCF7 Brivanib
0.37
uM
LJP5
 3
P16
 72
hr
 1235 3433 4156 0.8260 0.7524
MCF7 Buparlisib
0.37
uM
LJP5
 1
H04
 72
hr
 1235 1438 4156 0.3460 0.0694
MCF7 Buparlisib
0.37
uM
LJP5
 2
H04
 72
hr
 1235 1653 4156 0.3977 0.1430
MCF7 Buparlisib
0.37
uM
LJP5
 3
H04
 72
hr
 1235 1495 4156 0.3597 0.0889
MCF7 BX-912
0.37
uM
LJP5
 1
L22
 72
hr
 1235 3185 4156 0.7663 0.6675
MCF7 BX-912
0.37
uM
LJP5
 2
L22
 72
hr
 1235 3324 4156 0.7998 0.7151
MCF7 BX-912
0.37
uM
LJP5
 3
L22
 72
hr
 1235 3509 4156 0.8443 0.7784
MCF7 Canertinib
0.37
uM
LJP6
 1
H10
 72
hr
 1235 3190 4156 0.7675 0.6692
MCF7 Canertinib
0.37
uM
LJP6
 2
H10
 72
hr
 1235 2992 4156 0.7199 0.6014
MCF7 Canertinib
0.37
uM
LJP6
 3
H10
 72
hr
 1235 3401 4156 0.8183 0.7415
MCF7 Celastrol
0.37
uM
LJP6
 1
G10
 72
hr
 1235 1982 4156 0.4769 0.2556
MCF7 Celastrol
0.37
uM
LJP6
 2
G10
 72
hr
 1235 1944 4156 0.4677 0.2426
MCF7 Celastrol
0.37
uM
LJP6
 3
G10
 72
hr
 1235 2217 4156 0.5334 0.3361
MCF7 CGP60474
0.37
uM
LJP5
 1
F04
 72
hr
 1235 761 4156 0.1831 -0.1624
MCF7 CGP60474
0.37
uM
LJP5
 2
F04
 72
hr
 1235 816 4156 0.1963 -0.1436
MCF7 CGP60474
0.37
uM
LJP5
 3
F04
 72
hr
 1235 755 4156 0.1817 -0.1645
MCF7 CGP60474
0.37
uM
LJP6
 1
G04
 72
hr
 1235 547 4156 0.1316 -0.2357