LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 PIK-93
0.37
uM
LJP5
 3
K16
 72
hr
 1235 5327 4156 1.2817 1.4009
MCF7 KIN001-043
0.37
uM
LJP6
 1
C10
 72
hr
 1235 3739 4156 0.8996 0.8572
MCF7 KIN001-043
0.37
uM
LJP6
 2
C10
 72
hr
 1235 4080 4156 0.9817 0.9739
MCF7 KIN001-043
0.37
uM
LJP6
 3
C10
 72
hr
 1235 3749 4156 0.9020 0.8606
MCF7 Alpelisib
0.37
uM
LJP5
 1
N04
 72
hr
 1235 2742 4156 0.6597 0.5158
MCF7 Alpelisib
0.37
uM
LJP5
 2
N04
 72
hr
 1235 2668 4156 0.6419 0.4905
MCF7 Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 1235 2632 4156 0.6333 0.4782
MCF7 Luminespib
0.37
uM
LJP5
 1
H16
 72
hr
 1235 1367 4156 0.3289 0.0451
MCF7 Luminespib
0.37
uM
LJP5
 2
H16
 72
hr
 1235 1563 4156 0.3761 0.1122
MCF7 Luminespib
0.37
uM
LJP5
 3
H16
 72
hr
 1235 1489 4156 0.3583 0.0868
MCF7 A443654
0.37
uM
LJP6
 1
I22
 72
hr
 1235 848 4156 0.2040 -0.1326
MCF7 A443654
0.37
uM
LJP6
 2
I22
 72
hr
 1235 782 4156 0.1882 -0.1552
MCF7 A443654
0.37
uM
LJP6
 3
I22
 72
hr
 1235 885 4156 0.2129 -0.1200
MCF7 OSI-027
0.37
uM
LJP6
 1
E10
 72
hr
 1235 1860 4156 0.4475 0.2139
MCF7 OSI-027
0.37
uM
LJP6
 2
E10
 72
hr
 1235 2218 4156 0.5337 0.3364
MCF7 OSI-027
0.37
uM
LJP6
 3
E10
 72
hr
 1235 2135 4156 0.5137 0.3080
MCF7 XMD11-85h
0.37
uM
LJP6
 1
P22
 72
hr
 1235 3970 4156 0.9552 0.9363
MCF7 XMD11-85h
0.37
uM
LJP6
 2
P22
 72
hr
 1235 3358 4156 0.8080 0.7267
MCF7 XMD11-85h
0.37
uM
LJP6
 3
P22
 72
hr
 1235 3471 4156 0.8351 0.7654
MCF7 HG-6-64-01
0.37
uM
LJP6
 1
M04
 72
hr
 1235 4395 4156 1.0575 1.0818
MCF7 HG-6-64-01
0.37
uM
LJP6
 2
M04
 72
hr
 1235 3817 4156 0.9184 0.8839
MCF7 HG-6-64-01
0.37
uM
LJP6
 3
M04
 72
hr
 1235 3757 4156 0.9040 0.8633
MCF7 WH-4-025
0.37
uM
LJP5
 1
O10
 72
hr
 1235 2018 4156 0.4855 0.2680
MCF7 WH-4-025
0.37
uM
LJP5
 2
O10
 72
hr
 1235 1908 4156 0.4591 0.2303
MCF7 WH-4-025
0.37
uM
LJP5
 3
O10
 72
hr
 1235 1977 4156 0.4757 0.2539