LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 AZD8330
0.37
uM
LJP5
 2
G22
 72
hr
 1235 2000 4156 0.4812 0.2618
MCF7 AZD8330
0.37
uM
LJP5
 3
G22
 72
hr
 1235 2166 4156 0.5212 0.3186
MCF7 Barasertib
0.37
uM
LJP5
 1
D10
 72
hr
 1235 1612 4156 0.3879 0.1289
MCF7 Barasertib
0.37
uM
LJP5
 2
D10
 72
hr
 1235 1560 4156 0.3754 0.1111
MCF7 Barasertib
0.37
uM
LJP5
 3
D10
 72
hr
 1235 1683 4156 0.4049 0.1533
MCF7 BI-2536
0.37
uM
LJP6
 1
D16
 72
hr
 1235 1441 4156 0.3467 0.0704
MCF7 BI-2536
0.37
uM
LJP6
 2
D16
 72
hr
 1235 1441 4156 0.3467 0.0704
MCF7 BI-2536
0.37
uM
LJP6
 3
D16
 72
hr
 1235 1509 4156 0.3631 0.0937
MCF7 BMS345541
0.37
uM
LJP6
 1
D04
 72
hr
 1235 4172 4156 1.0038 1.0054
MCF7 BMS345541
0.37
uM
LJP6
 2
D04
 72
hr
 1235 3071 4156 0.7389 0.6285
MCF7 BMS345541
0.37
uM
LJP6
 3
D04
 72
hr
 1235 4056 4156 0.9759 0.9657
MCF7 SNS-032
0.37
uM
LJP6
 1
H16
 72
hr
 1235 486 4156 0.1169 -0.2566
MCF7 SNS-032
0.37
uM
LJP6
 2
H16
 72
hr
 1235 680 4156 0.1636 -0.1902
MCF7 SNS-032
0.37
uM
LJP6
 3
H16
 72
hr
 1235 558 4156 0.1343 -0.2319
MCF7 GDC-0980
0.37
uM
LJP5
 1
K22
 72
hr
 1235 1157 4156 0.2784 -0.0268
MCF7 GDC-0980
0.37
uM
LJP5
 2
K22
 72
hr
 1235 1131 4156 0.2721 -0.0357
MCF7 GDC-0980
0.37
uM
LJP5
 3
K22
 72
hr
 1235 1055 4156 0.2538 -0.0618
MCF7 NVP-AEW541
0.37
uM
LJP5
 1
E16
 72
hr
 1235 2588 4156 0.6227 0.4631
MCF7 NVP-AEW541
0.37
uM
LJP5
 2
E16
 72
hr
 1235 2469 4156 0.5941 0.4224
MCF7 NVP-AEW541
0.37
uM
LJP5
 3
E16
 72
hr
 1235 2572 4156 0.6188 0.4576
MCF7 SB590885
0.37
uM
LJP5
 1
L16
 72
hr
 1235 4192 4156 1.0086 1.0123
MCF7 SB590885
0.37
uM
LJP5
 2
L16
 72
hr
 1235 4833 4156 1.1629 1.2317
MCF7 SB590885
0.37
uM
LJP5
 3
L16
 72
hr
 1235 4900 4156 1.1790 1.2547
MCF7 PIK-93
0.37
uM
LJP5
 1
K16
 72
hr
 1235 4664 4156 1.1222 1.1739
MCF7 PIK-93
0.37
uM
LJP5
 2
K16
 72
hr
 1235 5077 4156 1.2216 1.3153