LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Sigma A6730 | 1.11 | uM | LJP5 | 3 | B21 | 72 | hr | 1235 | 2347 | 4156 | 0.5647 | 0.3806 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 1 | A15 | 72 | hr | 1235 | 609 | 4156 | 0.1465 | -0.2145 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 2 | A15 | 72 | hr | 1235 | 521 | 4156 | 0.1254 | -0.2446 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 3 | A15 | 72 | hr | 1235 | 589 | 4156 | 0.1417 | -0.2213 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 1 | K03 | 72 | hr | 1235 | 848 | 4156 | 0.2040 | -0.1326 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 2 | K03 | 72 | hr | 1235 | 910 | 4156 | 0.2190 | -0.1114 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 3 | K03 | 72 | hr | 1235 | 826 | 4156 | 0.1987 | -0.1402 |
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 1 | J03 | 72 | hr | 1235 | 1223 | 4156 | 0.2943 | -0.0042 |
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 2 | J03 | 72 | hr | 1235 | 1145 | 4156 | 0.2755 | -0.0309 |
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 3 | J03 | 72 | hr | 1235 | 1208 | 4156 | 0.2907 | -0.0094 |
| MCF7 | AZD-6482 | 1.11 | uM | LJP5 | 1 | I03 | 72 | hr | 1235 | 3911 | 4156 | 0.9410 | 0.9161 |
| MCF7 | AZD-6482 | 1.11 | uM | LJP5 | 2 | I03 | 72 | hr | 1235 | 4127 | 4156 | 0.9930 | 0.9900 |
| MCF7 | AZD-6482 | 1.11 | uM | LJP5 | 3 | I03 | 72 | hr | 1235 | 3981 | 4156 | 0.9579 | 0.9400 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 1 | L03 | 72 | hr | 1235 | 1294 | 4156 | 0.3113 | 0.0201 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 2 | L03 | 72 | hr | 1235 | 1272 | 4156 | 0.3061 | 0.0125 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 3 | L03 | 72 | hr | 1235 | 1365 | 4156 | 0.3284 | 0.0444 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 1 | A09 | 72 | hr | 1235 | 1397 | 4156 | 0.3361 | 0.0553 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 2 | A09 | 72 | hr | 1235 | 1227 | 4156 | 0.2952 | -0.0029 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 3 | A09 | 72 | hr | 1235 | 1251 | 4156 | 0.3010 | 0.0053 |
| MCF7 | AZD8330 | 1.11 | uM | LJP5 | 1 | G21 | 72 | hr | 1235 | 2287 | 4156 | 0.5503 | 0.3601 |
| MCF7 | AZD8330 | 1.11 | uM | LJP5 | 2 | G21 | 72 | hr | 1235 | 2174 | 4156 | 0.5231 | 0.3214 |
| MCF7 | AZD8330 | 1.11 | uM | LJP5 | 3 | G21 | 72 | hr | 1235 | 2715 | 4156 | 0.6533 | 0.5066 |
| MCF7 | Barasertib | 1.11 | uM | LJP5 | 1 | D09 | 72 | hr | 1235 | 1541 | 4156 | 0.3708 | 0.1046 |
| MCF7 | Barasertib | 1.11 | uM | LJP5 | 2 | D09 | 72 | hr | 1235 | 1517 | 4156 | 0.3650 | 0.0964 |
| MCF7 | Barasertib | 1.11 | uM | LJP5 | 3 | D09 | 72 | hr | 1235 | 1585 | 4156 | 0.3814 | 0.1197 |