LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF7 Dovitinib
0.37
uM
LJP5
 3
E22
 72
hr
 1235 3093 4156 0.7442 0.6360
MCF7 Enzastaurin
0.37
uM
LJP5
 1
D16
 72
hr
 1235 4423 4156 1.0642 1.0914
MCF7 Enzastaurin
0.37
uM
LJP5
 2
D16
 72
hr
 1235 4239 4156 1.0199 1.0284
MCF7 Enzastaurin
0.37
uM
LJP5
 3
D16
 72
hr
 1235 4395 4156 1.0575 1.0818
MCF7 Erlotinib
0.37
uM
LJP5
 1
M22
 72
hr
 1235 4247 4156 1.0219 1.0311
MCF7 Erlotinib
0.37
uM
LJP5
 2
M22
 72
hr
 1235 4484 4156 1.0789 1.1122
MCF7 Erlotinib
0.37
uM
LJP5
 3
M22
 72
hr
 1235 4295 4156 1.0334 1.0475
MCF7 Foretinib
0.37
uM
LJP5
 1
H10
 72
hr
 1235 1428 4156 0.3436 0.0659
MCF7 Foretinib
0.37
uM
LJP5
 2
H10
 72
hr
 1235 1665 4156 0.4006 0.1471
MCF7 Foretinib
0.37
uM
LJP5
 3
H10
 72
hr
 1235 1477 4156 0.3554 0.0827
MCF7 R406
0.37
uM
LJP6
 1
C16
 72
hr
 1235 3581 4156 0.8616 0.8031
MCF7 R406
0.37
uM
LJP6
 2
C16
 72
hr
 1235 3741 4156 0.9001 0.8579
MCF7 R406
0.37
uM
LJP6
 3
C16
 72
hr
 1235 3523 4156 0.8477 0.7832
MCF7 Pictilisib
0.37
uM
LJP6
 1
D22
 72
hr
 1235 1280 4156 0.3080 0.0153
MCF7 Pictilisib
0.37
uM
LJP6
 2
D22
 72
hr
 1235 1149 4156 0.2765 -0.0296
MCF7 Pictilisib
0.37
uM
LJP6
 3
D22
 72
hr
 1235 1180 4156 0.2839 -0.0190
MCF7 Gefitinib
0.37
uM
LJP6
 1
N10
 72
hr
 1235 4997 4156 1.2023 1.2879
MCF7 Gefitinib
0.37
uM
LJP6
 2
N10
 72
hr
 1235 3864 4156 0.9297 0.9000
MCF7 Gefitinib
0.37
uM
LJP6
 3
N10
 72
hr
 1235 4732 4156 1.1385 1.1972
MCF7 Geldanamycin
0.37
uM
LJP5
 1
O04
 72
hr
 1235 1301 4156 0.3130 0.0225
MCF7 Geldanamycin
0.37
uM
LJP5
 2
O04
 72
hr
 1235 1399 4156 0.3366 0.0560
MCF7 Geldanamycin
0.37
uM
LJP5
 3
O04
 72
hr
 1235 1486 4156 0.3575 0.0858
MCF7 Geldanamycin
0.37
uM
LJP6
 1
O04
 72
hr
 1235 1344 4156 0.3234 0.0372
MCF7 Geldanamycin
0.37
uM
LJP6
 2
O04
 72
hr
 1235 1233 4156 0.2967 -0.0008
MCF7 Geldanamycin
0.37
uM
LJP6
 3
O04
 72
hr
 1235 1386 4156 0.3335 0.0516