LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Celastrol | 0.12 | uM | LJP6 | 3 | G11 | 72 | hr | 513 | 12164 | 10401 | 1.1695 | 1.1783 |
| MCF 10A | Sorafenib | 0.04 | uM | LJP6 | 3 | B12 | 72 | hr | 513 | 12106 | 10401 | 1.1639 | 1.1724 |
| MCF 10A | Celastrol | 0.04 | uM | LJP6 | 3 | G12 | 72 | hr | 513 | 11985 | 10401 | 1.1523 | 1.1602 |
| MCF 10A | Celastrol | 0.04 | uM | LJP6 | 2 | G12 | 72 | hr | 513 | 11882 | 10401 | 1.1424 | 1.1498 |
| MCF 10A | Celastrol | 0.12 | uM | LJP6 | 2 | G11 | 72 | hr | 513 | 11871 | 10401 | 1.1413 | 1.1487 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 2 | J12 | 72 | hr | 513 | 11790 | 10401 | 1.1335 | 1.1405 |
| MCF 10A | PLX-4720 | 1.11 | uM | LJP5 | 1 | K03 | 72 | hr | 513 | 11759 | 10401 | 1.1305 | 1.1373 |
| MCF 10A | PLX-4720 | 1.11 | uM | LJP5 | 2 | K03 | 72 | hr | 513 | 11743 | 10401 | 1.1290 | 1.1357 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 1 | J12 | 72 | hr | 513 | 11680 | 10401 | 1.1230 | 1.1293 |
| MCF 10A | KIN001-043 | 0.04 | uM | LJP6 | 3 | C12 | 72 | hr | 513 | 11620 | 10401 | 1.1172 | 1.1233 |
| MCF 10A | NU7441 | 0.04 | uM | LJP5 | 3 | C12 | 72 | hr | 513 | 11595 | 10401 | 1.1148 | 1.1207 |
| MCF 10A | CP724714 | 0.04 | uM | LJP5 | 3 | A12 | 72 | hr | 513 | 11568 | 10401 | 1.1122 | 1.1180 |
| MCF 10A | Sorafenib | 0.04 | uM | LJP6 | 1 | B12 | 72 | hr | 513 | 11484 | 10401 | 1.1041 | 1.1095 |
| MCF 10A | Nintedanib | 0.04 | uM | LJP6 | 1 | H06 | 72 | hr | 513 | 11473 | 10401 | 1.1031 | 1.1084 |
| MCF 10A | Imatinib | 3.33 | uM | LJP6 | 2 | N14 | 72 | hr | 513 | 11470 | 10401 | 1.1028 | 1.1081 |
| MCF 10A | HG-6-64-01 | 0.04 | uM | LJP6 | 1 | M06 | 72 | hr | 513 | 11400 | 10401 | 1.0960 | 1.1010 |
| MCF 10A | PLX-4720 | 0.37 | uM | LJP5 | 2 | K04 | 72 | hr | 513 | 11400 | 10401 | 1.0960 | 1.1010 |
| MCF 10A | Imatinib | 3.33 | uM | LJP6 | 1 | N14 | 72 | hr | 513 | 11387 | 10401 | 1.0948 | 1.0997 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 1 | J11 | 72 | hr | 513 | 11384 | 10401 | 1.0945 | 1.0994 |
| MCF 10A | Imatinib | 10.0 | uM | LJP6 | 1 | N13 | 72 | hr | 513 | 11371 | 10401 | 1.0932 | 1.0981 |
| MCF 10A | Foretinib | 0.04 | uM | LJP5 | 3 | H12 | 72 | hr | 513 | 11369 | 10401 | 1.0931 | 1.0979 |
| MCF 10A | Saracatinib | 0.04 | uM | LJP6 | 3 | D12 | 72 | hr | 513 | 11303 | 10401 | 1.0867 | 1.0912 |
| MCF 10A | Imatinib | 1.11 | uM | LJP6 | 2 | N15 | 72 | hr | 513 | 11283 | 10401 | 1.0848 | 1.0892 |
| MCF 10A | TWS119 | 0.37 | uM | LJP5 | 2 | M04 | 72 | hr | 513 | 11280 | 10401 | 1.0845 | 1.0889 |
| MCF 10A | TWS119 | 0.04 | uM | LJP5 | 2 | M06 | 72 | hr | 513 | 11259 | 10401 | 1.0825 | 1.0868 |