LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 1235 | 1120 | 4156 | 0.2695 | -0.0395 |
| MCF7 | CP724714 | 10.0 | uM | LJP5 | 2 | A07 | 72 | hr | 1235 | 2057 | 4156 | 0.4949 | 0.2813 |
| MCF 10A | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 513 | 761 | 10401 | 0.0732 | 0.0250 |
| MCF7 | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 1235 | 1197 | 4156 | 0.2880 | -0.0131 |
| MCF7 | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 1235 | 1032 | 4156 | 0.2483 | -0.0696 |
| MCF7 | CP724714 | 10.0 | uM | LJP5 | 1 | A07 | 72 | hr | 1235 | 2139 | 4156 | 0.5147 | 0.3094 |
| MCF 10A | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 513 | 887 | 10401 | 0.0853 | 0.0378 |
| MCF 10A | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 513 | 872 | 10401 | 0.0838 | 0.0363 |
| MCF 10A | CP724714 | 10.0 | uM | LJP5 | 1 | A07 | 72 | hr | 513 | 8692 | 10401 | 0.8357 | 0.8272 |
| MCF 10A | CP724714 | 10.0 | uM | LJP5 | 3 | A07 | 72 | hr | 513 | 9231 | 10401 | 0.8875 | 0.8817 |
| Hs 578T | CP724714 | 10.0 | uM | LJP5 | 2 | A07 | 72 | hr | 929 | 2799 | 3228 | 0.8671 | 0.8134 |
| Hs 578T | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 929 | 931 | 3228 | 0.2884 | 0.0008 |
| Hs 578T | CP724714 | 10.0 | uM | LJP5 | 1 | A07 | 72 | hr | 929 | 2806 | 3228 | 0.8693 | 0.8164 |
| BT-20 | CP724714 | 10.0 | uM | LJP5 | 2 | A07 | 72 | hr | 1657 | 3683 | 5505 | 0.6690 | 0.5263 |
| Hs 578T | CP724714 | 10.0 | uM | LJP5 | 3 | A07 | 72 | hr | 929 | 2948 | 3228 | 0.9132 | 0.8782 |
| Hs 578T | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 929 | 1022 | 3228 | 0.3166 | 0.0403 |
| BT-20 | CP724714 | 10.0 | uM | LJP5 | 3 | A07 | 72 | hr | 1657 | 3845 | 5505 | 0.6984 | 0.5684 |
| BT-20 | CP724714 | 10.0 | uM | LJP5 | 1 | A07 | 72 | hr | 1657 | 3512 | 5505 | 0.6379 | 0.4819 |
| BT-20 | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 1657 | 1368 | 5505 | 0.2485 | -0.0753 |
| BT-20 | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 1657 | 1667 | 5505 | 0.3028 | 0.0024 |
| BT-20 | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 1657 | 1490 | 5505 | 0.2706 | -0.0436 |
| MCF 10A | CP724714 | 10.0 | uM | LJP5 | 2 | A07 | 72 | hr | 513 | 9166 | 10401 | 0.8813 | 0.8751 |
| Hs 578T | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 929 | 1084 | 3228 | 0.3358 | 0.0673 |
| MDA-MB-231 | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 868 | 1102 | 3486 | 0.3161 | 0.0893 |
| MCF7 | CP724714 | 10.0 | uM | LJP5 | 3 | A07 | 72 | hr | 1235 | 2135 | 4156 | 0.5137 | 0.3080 |