LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | LDN-193189 | 10.0 | uM | LJP5 | 3 | G01 | 72 | hr | 513 | 114 | 10401 | 0.0110 | -0.0404 |
| MCF 10A | LDN-193189 | 10.0 | uM | LJP5 | 1 | G01 | 72 | hr | 513 | 130 | 10401 | 0.0125 | -0.0388 |
| MCF 10A | LDN-193189 | 10.0 | uM | LJP5 | 2 | G01 | 72 | hr | 513 | 153 | 10401 | 0.0147 | -0.0364 |
| MCF 10A | Canertinib | 10.0 | uM | LJP6 | 2 | H07 | 72 | hr | 513 | 158 | 10401 | 0.0152 | -0.0359 |
| MCF 10A | Canertinib | 10.0 | uM | LJP6 | 3 | H07 | 72 | hr | 513 | 162 | 10401 | 0.0156 | -0.0355 |
| MCF 10A | Dasatinib | 10.0 | uM | LJP6 | 2 | I01 | 72 | hr | 513 | 198 | 10401 | 0.0190 | -0.0319 |
| MCF 10A | Dasatinib | 10.0 | uM | LJP6 | 1 | I01 | 72 | hr | 513 | 200 | 10401 | 0.0192 | -0.0317 |
| MCF 10A | HG-6-64-01 | 10.0 | uM | LJP6 | 1 | M01 | 72 | hr | 513 | 204 | 10401 | 0.0196 | -0.0313 |
| MCF 10A | Geldanamycin | 10.0 | uM | LJP6 | 2 | O01 | 72 | hr | 513 | 223 | 10401 | 0.0214 | -0.0294 |
| MCF 10A | Withaferin A | 10.0 | uM | LJP6 | 1 | G13 | 72 | hr | 513 | 236 | 10401 | 0.0227 | -0.0281 |
| MCF 10A | HG-6-64-01 | 10.0 | uM | LJP6 | 2 | M01 | 72 | hr | 513 | 241 | 10401 | 0.0232 | -0.0275 |
| MCF 10A | Withaferin A | 10.0 | uM | LJP5 | 1 | G13 | 72 | hr | 513 | 248 | 10401 | 0.0238 | -0.0268 |
| MCF 10A | Dasatinib | 10.0 | uM | LJP6 | 3 | I01 | 72 | hr | 513 | 253 | 10401 | 0.0243 | -0.0263 |
| MCF 10A | Dasatinib | 3.33 | uM | LJP6 | 2 | I02 | 72 | hr | 513 | 254 | 10401 | 0.0244 | -0.0262 |
| MCF 10A | GSK1059615 | 10.0 | uM | LJP5 | 1 | E01 | 72 | hr | 513 | 258 | 10401 | 0.0248 | -0.0258 |
| MCF 10A | GSK1059615 | 10.0 | uM | LJP6 | 2 | C01 | 72 | hr | 513 | 260 | 10401 | 0.0250 | -0.0256 |
| MCF 10A | Geldanamycin | 10.0 | uM | LJP5 | 3 | O01 | 72 | hr | 513 | 273 | 10401 | 0.0262 | -0.0243 |
| MCF 10A | GSK1059615 | 3.33 | uM | LJP5 | 1 | E02 | 72 | hr | 513 | 275 | 10401 | 0.0264 | -0.0241 |
| MCF 10A | GSK1059615 | 10.0 | uM | LJP5 | 3 | E01 | 72 | hr | 513 | 280 | 10401 | 0.0269 | -0.0236 |
| MCF 10A | Geldanamycin | 10.0 | uM | LJP6 | 1 | O01 | 72 | hr | 513 | 280 | 10401 | 0.0269 | -0.0236 |
| MCF 10A | Geldanamycin | 10.0 | uM | LJP6 | 3 | O01 | 72 | hr | 513 | 283 | 10401 | 0.0272 | -0.0233 |
| MCF 10A | Radicicol | 10.0 | uM | LJP5 | 3 | K07 | 72 | hr | 513 | 284 | 10401 | 0.0273 | -0.0232 |
| MCF 10A | Withaferin A | 3.33 | uM | LJP6 | 1 | G14 | 72 | hr | 513 | 290 | 10401 | 0.0279 | -0.0226 |
| MCF 10A | Afatinib | 0.04 | uM | LJP6 | 2 | G24 | 72 | hr | 513 | 293 | 10401 | 0.0282 | -0.0223 |
| MCF 10A | HG-6-64-01 | 10.0 | uM | LJP6 | 3 | M01 | 72 | hr | 513 | 293 | 10401 | 0.0282 | -0.0223 |