LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 1 | G09 | 72 | hr | 1476 | 4824 | 3694 | 1.3059 | 1.5096 |
| MCF7 | LDN-193189 | 0.04 | uM | LJP5 | 3 | G06 | 72 | hr | 1235 | 5439 | 4156 | 1.3087 | 1.4392 |
| SK-BR-3 | PD173074 | 0.04 | uM | LJP6 | 3 | I12 | 72 | hr | 1476 | 4626 | 3694 | 1.2523 | 1.4203 |
| MCF7 | Pelitinib | 0.12 | uM | LJP5 | 3 | I17 | 72 | hr | 1235 | 5374 | 4156 | 1.2930 | 1.4170 |
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 1 | G10 | 72 | hr | 1476 | 4585 | 3694 | 1.2412 | 1.4018 |
| MCF7 | PIK-93 | 0.37 | uM | LJP5 | 3 | K16 | 72 | hr | 1235 | 5327 | 4156 | 1.2817 | 1.4009 |
| SK-BR-3 | XL147 | 3.33 | uM | LJP5 | 1 | G08 | 72 | hr | 1476 | 4575 | 3694 | 1.2385 | 1.3973 |
| SK-BR-3 | PLX-4720 | 0.37 | uM | LJP5 | 1 | K04 | 72 | hr | 1476 | 4559 | 3694 | 1.2341 | 1.3901 |
| BT-20 | Enzastaurin | 3.33 | uM | LJP5 | 3 | D14 | 72 | hr | 1657 | 6985 | 5505 | 1.2687 | 1.3844 |
| MCF7 | PIK-93 | 0.12 | uM | LJP5 | 2 | K17 | 72 | hr | 1235 | 5275 | 4156 | 1.2692 | 1.3831 |
| Hs 578T | Sorafenib | 1.11 | uM | LJP6 | 2 | B09 | 72 | hr | 929 | 4101 | 3228 | 1.2704 | 1.3797 |
| BT-20 | Enzastaurin | 10.0 | uM | LJP5 | 3 | D13 | 72 | hr | 1657 | 6961 | 5505 | 1.2643 | 1.3782 |
| BT-20 | Enzastaurin | 10.0 | uM | LJP5 | 2 | D13 | 72 | hr | 1657 | 6961 | 5505 | 1.2643 | 1.3782 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 3 | G09 | 72 | hr | 1476 | 4524 | 3694 | 1.2247 | 1.3743 |
| SK-BR-3 | CP466722 | 0.04 | uM | LJP5 | 1 | I12 | 72 | hr | 1476 | 4520 | 3694 | 1.2236 | 1.3725 |
| SK-BR-3 | Seliciclib | 0.04 | uM | LJP5 | 1 | J06 | 72 | hr | 1476 | 4518 | 3694 | 1.2230 | 1.3716 |
| SK-BR-3 | SU11274 | 0.04 | uM | LJP5 | 1 | J12 | 72 | hr | 1476 | 4513 | 3694 | 1.2217 | 1.3693 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 3 | J12 | 72 | hr | 1235 | 5229 | 4156 | 1.2581 | 1.3673 |
| MCF7 | CP466722 | 0.37 | uM | LJP5 | 2 | I10 | 72 | hr | 1235 | 5225 | 4156 | 1.2572 | 1.3659 |
| SK-BR-3 | PD173074 | 0.12 | uM | LJP6 | 3 | I11 | 72 | hr | 1476 | 4486 | 3694 | 1.2144 | 1.3572 |
| Hs 578T | Sorafenib | 1.11 | uM | LJP6 | 3 | B09 | 72 | hr | 929 | 4045 | 3228 | 1.2531 | 1.3554 |
| Hs 578T | Sorafenib | 1.11 | uM | LJP6 | 1 | B09 | 72 | hr | 929 | 4036 | 3228 | 1.2503 | 1.3515 |
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 2 | M06 | 72 | hr | 1476 | 4473 | 3694 | 1.2109 | 1.3513 |
| SK-BR-3 | SB590885 | 0.37 | uM | LJP5 | 1 | L16 | 72 | hr | 1476 | 4469 | 3694 | 1.2098 | 1.3495 |
| SK-BR-3 | XL147 | 0.12 | uM | LJP5 | 1 | G11 | 72 | hr | 1476 | 4465 | 3694 | 1.2087 | 1.3477 |