LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 HG-5-113-01
10.0
uM
LJP5
 3
B07
 72
hr
 868 987 3486 0.2831 0.0454
MDA-MB-231 HG-5-88-01
10.0
uM
LJP6
 1
A19
 72
hr
 868 1684 3486 0.4830 0.3116
MDA-MB-231 HG-5-88-01
10.0
uM
LJP6
 2
A19
 72
hr
 868 1445 3486 0.4145 0.2203
MDA-MB-231 HG-5-88-01
10.0
uM
LJP6
 3
A19
 72
hr
 868 1687 3486 0.4839 0.3128
MDA-MB-231 Imatinib
10.0
uM
LJP6
 1
N13
 72
hr
 868 3242 3486 0.9299 0.9067
MDA-MB-231 Imatinib
10.0
uM
LJP6
 2
N13
 72
hr
 868 3278 3486 0.9402 0.9204
MDA-MB-231 Imatinib
10.0
uM
LJP6
 3
N13
 72
hr
 868 3180 3486 0.9121 0.8830
MDA-MB-231 JNK-9L
10.0
uM
LJP6
 1
K19
 72
hr
 868 780 3486 0.2237 -0.0337
MDA-MB-231 JNK-9L
10.0
uM
LJP6
 2
K19
 72
hr
 868 862 3486 0.2473 -0.0023
MDA-MB-231 JNK-9L
10.0
uM
LJP6
 3
K19
 72
hr
 868 851 3486 0.2441 -0.0065
MDA-MB-231 JW-7-24-1
10.0
uM
LJP6
 1
B19
 72
hr
 868 849 3486 0.2435 -0.0073
MDA-MB-231 JW-7-24-1
10.0
uM
LJP6
 2
B19
 72
hr
 868 841 3486 0.2412 -0.0104
MDA-MB-231 JW-7-24-1
10.0
uM
LJP6
 3
B19
 72
hr
 868 940 3486 0.2696 0.0275
MDA-MB-231 Lapatinib
10.0
uM
LJP6
 1
M19
 72
hr
 868 2673 3486 0.7667 0.6893
MDA-MB-231 Lapatinib
10.0
uM
LJP6
 2
M19
 72
hr
 868 2590 3486 0.7429 0.6576
MDA-MB-231 Lapatinib
10.0
uM
LJP6
 3
M19
 72
hr
 868 2559 3486 0.7340 0.6458
MDA-MB-231 LDN-193189
10.0
uM
LJP5
 1
G01
 72
hr
 868 309 3486 0.0886 -0.2135
MDA-MB-231 LDN-193189
10.0
uM
LJP5
 2
G01
 72
hr
 868 332 3486 0.0952 -0.2048
MDA-MB-231 LDN-193189
10.0
uM
LJP5
 3
G01
 72
hr
 868 355 3486 0.1018 -0.1960
MDA-MB-231 Linifanib
10.0
uM
LJP6
 1
J07
 72
hr
 868 1231 3486 0.3531 0.1386
MDA-MB-231 Linifanib
10.0
uM
LJP6
 2
J07
 72
hr
 868 1470 3486 0.4216 0.2299
MDA-MB-231 Linifanib
10.0
uM
LJP6
 3
J07
 72
hr
 868 1413 3486 0.4053 0.2081
MDA-MB-231 Linsitinib
10.0
uM
LJP5
 1
O19
 72
hr
 868 2137 3486 0.6130 0.4846
MDA-MB-231 Linsitinib
10.0
uM
LJP5
 2
O19
 72
hr
 868 2276 3486 0.6528 0.5377
MDA-MB-231 Linsitinib
10.0
uM
LJP5
 3
O19
 72
hr
 868 2223 3486 0.6376 0.5175