LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Mitoxantrone
10.0
uM
LJP5
 1
C19
 72
hr
 868 309 3486 0.0886 -0.2135
MDA-MB-231 Mitoxantrone
10.0
uM
LJP5
 2
C19
 72
hr
 868 372 3486 0.1067 -0.1895
MDA-MB-231 Mitoxantrone
10.0
uM
LJP5
 3
C19
 72
hr
 868 312 3486 0.0895 -0.2124
MDA-MB-231 Mitoxantrone
10.0
uM
LJP6
 1
C19
 72
hr
 868 289 3486 0.0829 -0.2212
MDA-MB-231 Mitoxantrone
10.0
uM
LJP6
 2
C19
 72
hr
 868 305 3486 0.0875 -0.2151
MDA-MB-231 Mitoxantrone
10.0
uM
LJP6
 3
C19
 72
hr
 868 276 3486 0.0792 -0.2262
MDA-MB-231 MK2206
10.0
uM
LJP6
 1
F01
 72
hr
 868 1122 3486 0.3218 0.0970
MDA-MB-231 MK2206
10.0
uM
LJP6
 2
F01
 72
hr
 868 1014 3486 0.2908 0.0557
MDA-MB-231 MK2206
10.0
uM
LJP6
 3
F01
 72
hr
 868 1282 3486 0.3677 0.1581
MDA-MB-231 Neratinib
10.0
uM
LJP5
 1
A13
 72
hr
 868 722 3486 0.2071 -0.0558
MDA-MB-231 Neratinib
10.0
uM
LJP5
 2
A13
 72
hr
 868 664 3486 0.1905 -0.0780
MDA-MB-231 Neratinib
10.0
uM
LJP5
 3
A13
 72
hr
 868 759 3486 0.2177 -0.0417
MDA-MB-231 Nilotinib
10.0
uM
LJP5
 1
N13
 72
hr
 868 1123 3486 0.3221 0.0973
MDA-MB-231 Nilotinib
10.0
uM
LJP5
 2
N13
 72
hr
 868 1339 3486 0.3841 0.1798
MDA-MB-231 Nilotinib
10.0
uM
LJP5
 3
N13
 72
hr
 868 1245 3486 0.3571 0.1439
MDA-MB-231 Nintedanib
10.0
uM
LJP6
 1
H01
 72
hr
 868 582 3486 0.1669 -0.1093
MDA-MB-231 Nintedanib
10.0
uM
LJP6
 2
H01
 72
hr
 868 634 3486 0.1819 -0.0894
MDA-MB-231 Nintedanib
10.0
uM
LJP6
 3
H01
 72
hr
 868 708 3486 0.2031 -0.0612
MDA-MB-231 NU7441
10.0
uM
LJP5
 1
C07
 72
hr
 868 1152 3486 0.3304 0.1084
MDA-MB-231 NU7441
10.0
uM
LJP5
 2
C07
 72
hr
 868 1184 3486 0.3396 0.1206
MDA-MB-231 NU7441
10.0
uM
LJP5
 3
C07
 72
hr
 868 1143 3486 0.3279 0.1050
MDA-MB-231 Dactolisib
10.0
uM
LJP5
 1
M13
 72
hr
 868 1548 3486 0.4440 0.2597
MDA-MB-231 Dactolisib
10.0
uM
LJP5
 2
M13
 72
hr
 868 1561 3486 0.4477 0.2646
MDA-MB-231 Dactolisib
10.0
uM
LJP5
 3
M13
 72
hr
 868 1556 3486 0.4463 0.2627
MDA-MB-231 NVP-TAE684
10.0
uM
LJP6
 1
K13
 72
hr
 868 678 3486 0.1945 -0.0726