LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 NVP-TAE684
10.0
uM
LJP6
 2
K13
 72
hr
 868 687 3486 0.1971 -0.0692
MDA-MB-231 NVP-TAE684
10.0
uM
LJP6
 3
K13
 72
hr
 868 730 3486 0.2094 -0.0528
MDA-MB-231 Palbociclib
10.0
uM
LJP6
 1
E13
 72
hr
 868 1461 3486 0.4191 0.2264
MDA-MB-231 Palbociclib
10.0
uM
LJP6
 2
E13
 72
hr
 868 1462 3486 0.4193 0.2268
MDA-MB-231 Palbociclib
10.0
uM
LJP6
 3
E13
 72
hr
 868 1548 3486 0.4440 0.2597
MDA-MB-231 PD0325901
10.0
uM
LJP5
 1
C01
 72
hr
 868 832 3486 0.2386 -0.0138
MDA-MB-231 PD0325901
10.0
uM
LJP5
 2
C01
 72
hr
 868 932 3486 0.2673 0.0244
MDA-MB-231 PD0325901
10.0
uM
LJP5
 3
C01
 72
hr
 868 930 3486 0.2668 0.0236
MDA-MB-231 PD0325901
10.0
uM
LJP6
 1
E01
 72
hr
 868 762 3486 0.2186 -0.0405
MDA-MB-231 PD0325901
10.0
uM
LJP6
 2
E01
 72
hr
 868 740 3486 0.2123 -0.0489
MDA-MB-231 PD0325901
10.0
uM
LJP6
 3
E01
 72
hr
 868 978 3486 0.2805 0.0420
MDA-MB-231 PD173074
10.0
uM
LJP6
 1
I07
 72
hr
 868 1188 3486 0.3408 0.1222
MDA-MB-231 PD173074
10.0
uM
LJP6
 2
I07
 72
hr
 868 1347 3486 0.3864 0.1829
MDA-MB-231 PD173074
10.0
uM
LJP6
 3
I07
 72
hr
 868 1285 3486 0.3686 0.1592
MDA-MB-231 PD184352
10.0
uM
LJP5
 1
L07
 72
hr
 868 1373 3486 0.3938 0.1928
MDA-MB-231 PD184352
10.0
uM
LJP5
 2
L07
 72
hr
 868 1305 3486 0.3743 0.1669
MDA-MB-231 PD184352
10.0
uM
LJP5
 3
L07
 72
hr
 868 1401 3486 0.4019 0.2035
MDA-MB-231 Pelitinib
10.0
uM
LJP5
 1
I13
 72
hr
 868 691 3486 0.1982 -0.0676
MDA-MB-231 Pelitinib
10.0
uM
LJP5
 2
I13
 72
hr
 868 744 3486 0.2134 -0.0474
MDA-MB-231 Pelitinib
10.0
uM
LJP5
 3
I13
 72
hr
 868 704 3486 0.2019 -0.0627
MDA-MB-231 PF431396
10.0
uM
LJP5
 1
E07
 72
hr
 868 831 3486 0.2384 -0.0142
MDA-MB-231 PF431396
10.0
uM
LJP5
 2
E07
 72
hr
 868 874 3486 0.2507 0.0022
MDA-MB-231 PF431396
10.0
uM
LJP5
 3
E07
 72
hr
 868 941 3486 0.2699 0.0278
MDA-MB-231 PF477736
10.0
uM
LJP5
 1
J19
 72
hr
 868 1040 3486 0.2983 0.0656
MDA-MB-231 PF477736
10.0
uM
LJP5
 2
J19
 72
hr
 868 1067 3486 0.3061 0.0760