LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Dovitinib
0.04
uM
LJP5
 3
E24
 72
hr
 1476 2575 3694 0.6971 0.4953
SK-BR-3 Enzastaurin
0.04
uM
LJP5
 1
D18
 72
hr
 1476 4152 3694 1.1240 1.2065
SK-BR-3 Enzastaurin
0.04
uM
LJP5
 2
D18
 72
hr
 1476 4409 3694 1.1935 1.3224
SK-BR-3 Enzastaurin
0.04
uM
LJP5
 3
D18
 72
hr
 1476 4321 3694 1.1697 1.2827
SK-BR-3 Erlotinib
0.04
uM
LJP5
 1
M24
 72
hr
 1476 3297 3694 0.8925 0.8209
SK-BR-3 Erlotinib
0.04
uM
LJP5
 2
M24
 72
hr
 1476 2957 3694 0.8005 0.6676
SK-BR-3 Erlotinib
0.04
uM
LJP5
 3
M24
 72
hr
 1476 2840 3694 0.7688 0.6148
SK-BR-3 Foretinib
0.04
uM
LJP5
 1
H12
 72
hr
 1476 3965 3694 1.0733 1.1222
SK-BR-3 Foretinib
0.04
uM
LJP5
 2
H12
 72
hr
 1476 3988 3694 1.0796 1.1326
SK-BR-3 Foretinib
0.04
uM
LJP5
 3
H12
 72
hr
 1476 3912 3694 1.0590 1.0983
SK-BR-3 R406
0.04
uM
LJP6
 1
C18
 72
hr
 1476 3791 3694 1.0262 1.0437
SK-BR-3 R406
0.04
uM
LJP6
 2
C18
 72
hr
 1476 3673 3694 0.9943 0.9905
SK-BR-3 R406
0.04
uM
LJP6
 3
C18
 72
hr
 1476 4050 3694 1.0964 1.1605
SK-BR-3 Pictilisib
0.04
uM
LJP6
 1
D24
 72
hr
 1476 2074 3694 0.5614 0.2694
SK-BR-3 Pictilisib
0.04
uM
LJP6
 2
D24
 72
hr
 1476 2162 3694 0.5853 0.3091
SK-BR-3 Pictilisib
0.04
uM
LJP6
 3
D24
 72
hr
 1476 2337 3694 0.6326 0.3880
SK-BR-3 Gefitinib
0.04
uM
LJP6
 1
N12
 72
hr
 1476 3244 3694 0.8782 0.7970
SK-BR-3 Gefitinib
0.04
uM
LJP6
 2
N12
 72
hr
 1476 3536 3694 0.9572 0.9287
SK-BR-3 Gefitinib
0.04
uM
LJP6
 3
N12
 72
hr
 1476 3520 3694 0.9529 0.9215
SK-BR-3 Geldanamycin
0.04
uM
LJP5
 1
O06
 72
hr
 1476 1446 3694 0.3914 -0.0139
SK-BR-3 Geldanamycin
0.04
uM
LJP5
 2
O06
 72
hr
 1476 1403 3694 0.3798 -0.0332
SK-BR-3 Geldanamycin
0.04
uM
LJP5
 3
O06
 72
hr
 1476 1567 3694 0.4242 0.0407
SK-BR-3 Geldanamycin
0.04
uM
LJP6
 1
O06
 72
hr
 1476 1487 3694 0.4025 0.0046
SK-BR-3 Geldanamycin
0.04
uM
LJP6
 2
O06
 72
hr
 1476 1543 3694 0.4177 0.0299
SK-BR-3 Geldanamycin
0.04
uM
LJP6
 3
O06
 72
hr
 1476 1448 3694 0.3920 -0.0130