LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Geldanamycin
10.0
uM
LJP5
 2
O01
 72
hr
 868 529 3486 0.1517 -0.1295
MDA-MB-231 Geldanamycin
10.0
uM
LJP5
 3
O01
 72
hr
 868 643 3486 0.1844 -0.0860
MDA-MB-231 Geldanamycin
10.0
uM
LJP6
 1
O01
 72
hr
 868 582 3486 0.1669 -0.1093
MDA-MB-231 Geldanamycin
10.0
uM
LJP6
 2
O01
 72
hr
 868 532 3486 0.1526 -0.1284
MDA-MB-231 Geldanamycin
10.0
uM
LJP6
 3
O01
 72
hr
 868 551 3486 0.1580 -0.1211
MDA-MB-231 GSK1059615
10.0
uM
LJP5
 1
E01
 72
hr
 868 509 3486 0.1460 -0.1372
MDA-MB-231 GSK1059615
10.0
uM
LJP5
 2
E01
 72
hr
 868 558 3486 0.1601 -0.1184
MDA-MB-231 GSK1059615
10.0
uM
LJP5
 3
E01
 72
hr
 868 692 3486 0.1985 -0.0673
MDA-MB-231 GSK1059615
10.0
uM
LJP6
 1
C01
 72
hr
 868 582 3486 0.1669 -0.1093
MDA-MB-231 GSK1059615
10.0
uM
LJP6
 2
C01
 72
hr
 868 609 3486 0.1747 -0.0990
MDA-MB-231 GSK1059615
10.0
uM
LJP6
 3
C01
 72
hr
 868 790 3486 0.2266 -0.0298
MDA-MB-231 GSK1904529A
10.0
uM
LJP6
 1
H19
 72
hr
 868 3416 3486 0.9798 0.9731
MDA-MB-231 GSK1904529A
10.0
uM
LJP6
 2
H19
 72
hr
 868 3355 3486 0.9623 0.9498
MDA-MB-231 GSK1904529A
10.0
uM
LJP6
 3
H19
 72
hr
 868 3356 3486 0.9626 0.9502
MDA-MB-231 Omipalisib
10.0
uM
LJP6
 1
N01
 72
hr
 868 993 3486 0.2848 0.0477
MDA-MB-231 Omipalisib
10.0
uM
LJP6
 2
N01
 72
hr
 868 1225 3486 0.3514 0.1363
MDA-MB-231 Omipalisib
10.0
uM
LJP6
 3
N01
 72
hr
 868 875 3486 0.2510 0.0026
MDA-MB-231 GSK 690693
10.0
uM
LJP5
 1
F19
 72
hr
 868 3110 3486 0.8920 0.8562
MDA-MB-231 GSK 690693
10.0
uM
LJP5
 2
F19
 72
hr
 868 3134 3486 0.8989 0.8654
MDA-MB-231 GSK 690693
10.0
uM
LJP5
 3
F19
 72
hr
 868 3177 3486 0.9113 0.8818
MDA-MB-231 GW843682X
10.0
uM
LJP6
 1
B13
 72
hr
 868 1227 3486 0.3519 0.1371
MDA-MB-231 GW843682X
10.0
uM
LJP6
 2
B13
 72
hr
 868 1092 3486 0.3132 0.0855
MDA-MB-231 GW843682X
10.0
uM
LJP6
 3
B13
 72
hr
 868 1335 3486 0.3829 0.1783
MDA-MB-231 HG-5-113-01
10.0
uM
LJP5
 1
B07
 72
hr
 868 907 3486 0.2602 0.0149
MDA-MB-231 HG-5-113-01
10.0
uM
LJP5
 2
B07
 72
hr
 868 952 3486 0.2731 0.0320