PLSR model loadings (pMEK and pERK excluded) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20230)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| RVH-421 | 48 | hr | p-mTOR(S2448) | -1.22350 | -1.91150 |
| RVH-421 | 48 | hr | p-p70S6K(T421/S424) | 3.73260 | -0.88187 |
| RVH-421 | 48 | hr | p-p70S6K(T389) | -3.05730 | -1.98040 |
| RVH-421 | 48 | hr | p-S6(S235/236) | 2.58350 | -1.59580 |
| RVH-421 | 48 | hr | p-AMPK(T172) | -0.11719 | -2.28580 |
| RVH-421 | 48 | hr | p-JNK(T183/Y185) | NaN | NaN |
| RVH-421 | 48 | hr | Total c-Jun | -5.78540 | -1.36930 |
| RVH-421 | 48 | hr | p-cJun(S63) | -5.07940 | -1.56320 |
| RVH-421 | 48 | hr | p-P38(T180/Y182) | -0.29272 | 0.94950 |
| RVH-421 | 48 | hr | p-HSP27(S82) | -0.18051 | -2.07900 |
| RVH-421 | 48 | hr | p-NFKB(S536) | -1.81670 | -1.19220 |
| RVH-421 | 48 | hr | Bim | -2.95910 | -2.12480 |
| RVH-421 | 48 | hr | cPARP | -5.10520 | -0.85680 |
| RVH-421 | 48 | hr | p-Histone H3(S10) | 4.41860 | -0.02785 |
| RVH-421 | 48 | hr | p27 Kip1 | -3.70640 | -1.59780 |
| SKMEL28 | 1 | hr | p-p90RSK(S380) | 3.73980 | -0.75211 |
| SKMEL28 | 1 | hr | p-p90RSK(T573) | 1.92600 | 0.22715 |
| SKMEL28 | 1 | hr | p-AKT(T308) | NaN | NaN |
| SKMEL28 | 1 | hr | p-AKT(S473) | 2.05400 | -1.42740 |
| SKMEL28 | 1 | hr | p-mTOR(S2448) | 3.30170 | -0.83713 |
| SKMEL28 | 1 | hr | p-p70S6K(T421/S424) | 4.31910 | -1.13160 |
| SKMEL28 | 1 | hr | p-p70S6K(T389) | 2.60440 | 0.12610 |
| SKMEL28 | 1 | hr | p-S6(S235/236) | 1.80730 | -0.68467 |
| SKMEL28 | 1 | hr | p-AMPK(T172) | 0.40132 | 0.82183 |
| SKMEL28 | 1 | hr | p-JNK(T183/Y185) | 3.63970 | -2.58450 |