PLSR model loadings (pMEK and pERK excluded) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20230)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| RVH-421 | 10 | hr | p-Histone H3(S10) | 0.37980 | -1.15850 |
| RVH-421 | 10 | hr | p27 Kip1 | 2.39160 | -1.21100 |
| RVH-421 | 24 | hr | p-p90RSK(S380) | -4.16360 | 0.18941 |
| RVH-421 | 24 | hr | p-p90RSK(T573) | -4.03180 | 0.53033 |
| RVH-421 | 24 | hr | p-AKT(T308) | -1.93530 | -0.62917 |
| RVH-421 | 24 | hr | p-AKT(S473) | -0.28845 | 0.59934 |
| RVH-421 | 24 | hr | p-mTOR(S2448) | -2.84470 | -0.53386 |
| RVH-421 | 24 | hr | p-p70S6K(T421/S424) | 4.49300 | 0.13431 |
| RVH-421 | 24 | hr | p-p70S6K(T389) | -3.31400 | -0.14821 |
| RVH-421 | 24 | hr | p-S6(S235/236) | 3.81310 | 0.06714 |
| RVH-421 | 24 | hr | p-AMPK(T172) | -3.81420 | -1.15100 |
| RVH-421 | 24 | hr | p-JNK(T183/Y185) | NaN | NaN |
| RVH-421 | 24 | hr | Total c-Jun | -6.15220 | 0.71907 |
| RVH-421 | 24 | hr | p-cJun(S63) | -1.65730 | -0.94838 |
| RVH-421 | 24 | hr | p-P38(T180/Y182) | -1.08130 | 1.17850 |
| RVH-421 | 24 | hr | p-HSP27(S82) | -4.01440 | -1.00100 |
| RVH-421 | 24 | hr | p-NFKB(S536) | -5.06590 | -0.79803 |
| RVH-421 | 24 | hr | Bim | -4.65140 | -1.31240 |
| RVH-421 | 24 | hr | cPARP | -6.86810 | -0.15272 |
| RVH-421 | 24 | hr | p-Histone H3(S10) | 1.93280 | 1.15590 |
| RVH-421 | 24 | hr | p27 Kip1 | -5.29960 | -1.22490 |
| RVH-421 | 48 | hr | p-p90RSK(S380) | -2.42880 | -0.35683 |
| RVH-421 | 48 | hr | p-p90RSK(T573) | -2.50320 | -1.42660 |
| RVH-421 | 48 | hr | p-AKT(T308) | -2.72880 | -1.49920 |
| RVH-421 | 48 | hr | p-AKT(S473) | 1.04670 | -0.87478 |