PLSR model loadings (pMEK and pERK excluded) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20230)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| RVH-421 | 5 | hr | p-cJun(S63) | 0.50880 | -0.56270 |
| RVH-421 | 5 | hr | p-P38(T180/Y182) | 0.56510 | 0.42000 |
| RVH-421 | 5 | hr | p-HSP27(S82) | -3.99810 | -1.23350 |
| RVH-421 | 5 | hr | p-NFKB(S536) | -4.21610 | -1.61760 |
| RVH-421 | 5 | hr | Bim | -4.35800 | -1.65180 |
| RVH-421 | 5 | hr | cPARP | -2.66410 | -0.32543 |
| RVH-421 | 5 | hr | p-Histone H3(S10) | -4.18110 | -1.14260 |
| RVH-421 | 5 | hr | p27 Kip1 | -2.97350 | -0.94074 |
| RVH-421 | 10 | hr | p-p90RSK(S380) | 3.54790 | -0.53802 |
| RVH-421 | 10 | hr | p-p90RSK(T573) | 3.15960 | -0.60187 |
| RVH-421 | 10 | hr | p-AKT(T308) | 2.99020 | -1.69920 |
| RVH-421 | 10 | hr | p-AKT(S473) | 2.45620 | -0.76092 |
| RVH-421 | 10 | hr | p-mTOR(S2448) | 4.29420 | -1.97120 |
| RVH-421 | 10 | hr | p-p70S6K(T421/S424) | 4.66210 | -0.08991 |
| RVH-421 | 10 | hr | p-p70S6K(T389) | 4.08200 | -1.81700 |
| RVH-421 | 10 | hr | p-S6(S235/236) | 6.84770 | -0.58532 |
| RVH-421 | 10 | hr | p-AMPK(T172) | 4.95020 | -1.11860 |
| RVH-421 | 10 | hr | p-JNK(T183/Y185) | NaN | NaN |
| RVH-421 | 10 | hr | Total c-Jun | -2.76040 | 1.65400 |
| RVH-421 | 10 | hr | p-cJun(S63) | -0.23882 | -0.51951 |
| RVH-421 | 10 | hr | p-P38(T180/Y182) | -0.37356 | 1.48390 |
| RVH-421 | 10 | hr | p-HSP27(S82) | 3.95020 | -0.69340 |
| RVH-421 | 10 | hr | p-NFKB(S536) | 1.49720 | -1.00140 |
| RVH-421 | 10 | hr | Bim | 2.28110 | -2.60780 |
| RVH-421 | 10 | hr | cPARP | 0.65903 | -0.50797 |