PLSR model loadings (pMEK and pERK excluded) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20230)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| RVH-421 | 1 | hr | p-p70S6K(T421/S424) | 3.62530 | -0.53620 |
| RVH-421 | 1 | hr | p-p70S6K(T389) | 2.44110 | -0.93520 |
| RVH-421 | 1 | hr | p-S6(S235/236) | 2.11190 | -0.99144 |
| RVH-421 | 1 | hr | p-AMPK(T172) | 4.14660 | -2.28560 |
| RVH-421 | 1 | hr | p-JNK(T183/Y185) | NaN | NaN |
| RVH-421 | 1 | hr | Total c-Jun | 0.05915 | 0.67867 |
| RVH-421 | 1 | hr | p-cJun(S63) | -1.52200 | -0.50363 |
| RVH-421 | 1 | hr | p-P38(T180/Y182) | 1.40970 | 1.82360 |
| RVH-421 | 1 | hr | p-HSP27(S82) | 4.31950 | -1.64660 |
| RVH-421 | 1 | hr | p-NFKB(S536) | 3.91770 | -2.15360 |
| RVH-421 | 1 | hr | Bim | 1.78350 | -2.61950 |
| RVH-421 | 1 | hr | cPARP | 2.00760 | -0.45382 |
| RVH-421 | 1 | hr | p-Histone H3(S10) | 2.63930 | -2.21930 |
| RVH-421 | 1 | hr | p27 Kip1 | 3.29140 | -2.22920 |
| RVH-421 | 5 | hr | p-p90RSK(S380) | -3.96560 | 0.34135 |
| RVH-421 | 5 | hr | p-p90RSK(T573) | -4.10820 | -0.37161 |
| RVH-421 | 5 | hr | p-AKT(T308) | -3.28740 | -0.85704 |
| RVH-421 | 5 | hr | p-AKT(S473) | -2.85240 | 0.01422 |
| RVH-421 | 5 | hr | p-mTOR(S2448) | -4.19550 | -0.37471 |
| RVH-421 | 5 | hr | p-p70S6K(T421/S424) | 0.87377 | -0.32157 |
| RVH-421 | 5 | hr | p-p70S6K(T389) | -3.98450 | -0.39318 |
| RVH-421 | 5 | hr | p-S6(S235/236) | 1.60790 | -0.53602 |
| RVH-421 | 5 | hr | p-AMPK(T172) | -3.78820 | -1.09560 |
| RVH-421 | 5 | hr | p-JNK(T183/Y185) | NaN | NaN |
| RVH-421 | 5 | hr | Total c-Jun | -0.10371 | 0.77293 |