Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Nutlin 3a | HCC1428 | -4.1759 | 0.8744 | -4.3440 | -4.3440 | -4.5678 | 1.7185 | 0.0000 | 0.3378 | 8.0519 |
| Nutlin 3a | HCC1569 | -4.1759 | 0.9023 | -4.4159 | -4.4159 | -4.4193 | 1.6810 | 0.0001 | 0.2847 | 8.1346 |
| Nutlin 3a | HCC1806 | -4.1759 | 0.9708 | -4.4855 | -4.4855 | -4.3888 | 3.4330 | 0.0000 | 0.0796 | 8.2506 |
| Nutlin 3a | HCC1937 | -4.1759 | 0.8610 | -4.5521 | -4.4253 | -4.5974 | 2.8750 | 0.2258 | 0.3795 | 8.2752 |
| Nutlin 3a | HCC1954 | -4.1759 | 0.8726 | -4.6342 | -4.6342 | -4.7571 | 2.0590 | 0.0000 | 0.1027 | 7.4595 |
| Nutlin 3a | HCC202 | -4.1759 | 0.9273 | -4.2657 | -4.2657 | -4.3683 | 4.0000 | 0.0000 | 0.3043 | 8.3607 |
| Nutlin 3a | HCC38 | -4.1759 | 0.8404 | -4.5748 | -4.5564 | -4.6538 | 2.2060 | 0.0000 | 0.2906 | 8.0087 |
| Nutlin 3a | HCC70 | -4.1759 | 0.8237 | -4.4763 | -4.4763 | -4.7683 | 1.4990 | 0.0000 | 0.2617 | 7.7421 |
| Nutlin 3a | Hs 578T | -4.1759 | 0.8948 | -4.3104 | -4.3104 | -4.4057 | 1.1969 | 0.0000 | 0.4147 | 8.7475 |
| Nutlin 3a | MB 157 | -4.1759 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 9.1232 |
| Nutlin 3a | MDA-MB-134-VI | -4.1759 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.4955 |
| Nutlin 3a | MDA-MB-157 | -4.1759 | 0.9064 | -4.3947 | -4.3432 | -4.4637 | 3.9990 | 0.2124 | 0.4384 | 8.4537 |
| Nutlin 3a | MDA-MB-175-VII | -4.1759 | 0.7346 | -4.4642 | -4.2380 | -5.3052 | 0.7904 | 0.0000 | 0.4824 | 7.7723 |
| Nutlin 3a | MDA-MB-361 | -4.1759 | 0.9383 | -4.4644 | -4.4644 | -4.7199 | 2.0680 | 0.0000 | 0.2020 | 8.2309 |
| Nutlin 3a | MDA-MB-436 | -4.1759 | 0.7868 | -4.3292 | -4.3292 | -4.4743 | 1.3330 | 0.0000 | 0.3845 | 8.0455 |
| Nutlin 3a | MDA-MB-453 | -4.1759 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.3093 |
| Nutlin 3a | MDA-MB-468 | -4.1759 | 0.8861 | -4.3823 | -4.3663 | -4.4612 | 2.7015 | 0.0970 | 0.3628 | 8.2968 |
| Nutlin 3a | T47D | -4.1759 | 0.7382 | -4.0549 | -4.2805 | -4.5633 | 0.9696 | 0.0000 | 0.4870 | 7.8995 |
| Nutlin 3a | UACC-812 | -4.1759 | 0.8182 | -4.8178 | -4.5095 | -5.3750 | 1.0490 | 0.2625 | 0.3916 | 7.5355 |
| Nutlin 3a | UACC-893 | -4.1759 | 0.8050 | -4.3682 | -4.3017 | -4.4486 | 4.0000 | 0.2008 | 0.5057 | 8.5621 |
| Nutlin 3a | ZR-75-1 | -4.1759 | 0.9303 | -5.1144 | -4.9732 | -5.5622 | 0.7281 | 0.0742 | 0.2400 | 7.1870 |
| Nutlin 3a | 184B5 | -4.1759 | 0.9183 | -4.9725 | -4.9726 | -5.2634 | 1.6990 | 0.0000 | 0.1206 | 7.1532 |
| Nutlin 3a | HCC1187 | -4.1759 | 0.9250 | -4.6310 | -4.6309 | -4.7423 | 2.8760 | 0.0000 | 0.1656 | 8.0912 |
| Nutlin 3a | MCF 10A | -4.1759 | 0.9346 | -5.3169 | -5.1344 | -5.2479 | 0.9769 | 0.0000 | 0.1323 | 7.0415 |
| Nutlin 3a | MCF 10F | -4.1759 | 0.9000 | -5.0644 | -4.7920 | -5.1968 | 1.3978 | 0.1349 | 0.3398 | 7.4849 |