Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| NSC 663284 | HCC38 | -3.7773 | 0.9743 | -5.5708 | -5.5701 | -5.6970 | 2.0220 | 0.0014 | 0.0017 | 5.7308 |
| NSC 663284 | HCC70 | -3.7773 | 0.9588 | -5.2793 | -5.2775 | -5.5443 | 1.6650 | 0.0036 | 0.0080 | 6.2072 |
| NSC 663284 | Hs 578T | -3.7773 | 0.9913 | -5.7363 | -5.7357 | -5.7767 | 3.9980 | 0.0029 | 0.0029 | 5.7091 |
| NSC 663284 | MB 157 | -3.7773 | 0.9945 | -5.6313 | -5.6304 | -5.6766 | 4.0000 | 0.0034 | 0.0034 | 5.8731 |
| NSC 663284 | MDA-MB-134-VI | -3.7773 | 0.9715 | -5.0293 | -5.0290 | -5.1937 | 2.8900 | 0.0000 | 0.0002 | 6.5414 |
| NSC 663284 | MDA-MB-157 | -3.7773 | 0.9639 | -5.7633 | -5.7624 | -5.8555 | 3.9990 | 0.0018 | 0.0018 | 6.2600 |
| NSC 663284 | MDA-MB-175-VII | -3.7773 | 0.9657 | -5.0143 | -5.0133 | -5.2352 | 3.4390 | 0.0105 | 0.0105 | 6.4461 |
| NSC 663284 | MDA-MB-361 | -3.7773 | 0.9793 | -5.1003 | -5.0972 | -5.2837 | 4.0000 | 0.0013 | 0.0013 | 6.7724 |
| NSC 663284 | MDA-MB-436 | -3.7773 | 0.9605 | -5.1253 | -5.1257 | -5.4319 | 1.7520 | 0.0000 | 0.0043 | 6.5858 |
| NSC 663284 | MDA-MB-453 | -3.7773 | 0.9816 | -5.2453 | -5.2416 | -5.3496 | 4.0000 | 0.0150 | 0.0150 | 6.2119 |
| NSC 663284 | MDA-MB-468 | -3.7773 | 0.9547 | -5.1093 | -5.1095 | -5.2017 | 2.0150 | 0.0000 | 0.0021 | 6.3129 |
| NSC 663284 | T47D | -3.7773 | 0.9713 | -5.1153 | -5.1148 | -5.2160 | 2.7490 | 0.0000 | 0.0002 | 6.4644 |
| NSC 663284 | UACC-812 | -3.7773 | 0.9777 | -5.2943 | -5.2946 | -5.6379 | 1.5900 | 0.0000 | 0.0054 | 6.1324 |
| NSC 663284 | UACC-893 | -3.7773 | 0.9778 | -5.1113 | -5.1116 | -5.4701 | 2.4310 | 0.0000 | 0.0006 | 6.3380 |
| NSC 663284 | ZR-75-1 | -3.7773 | 0.9140 | -5.6198 | -5.6188 | -6.0060 | 1.4630 | 0.0018 | 0.0062 | 5.4328 |
| NSC 663284 | 184B5 | -3.7773 | 0.9787 | -5.5663 | -5.5629 | -5.6520 | 3.6940 | 0.0158 | 0.0158 | 6.1108 |
| NSC 663284 | HCC1187 | -3.7773 | 0.9799 | -5.6338 | -5.6327 | -5.7272 | 4.0000 | 0.0046 | 0.0046 | 5.7978 |
| NSC 663284 | MCF 10A | -3.7773 | 0.9765 | -5.6693 | -5.6674 | -5.7118 | 2.5110 | 0.0049 | 0.0049 | 5.7116 |
| NSC 663284 | MCF 10F | -3.7773 | 0.9813 | -5.4833 | -5.4833 | -5.6512 | 1.4940 | 0.0000 | 0.0028 | 5.8480 |
| NSC 663284 | SUM1315MO2 | -3.7773 | 0.9827 | -5.6958 | -5.6938 | -5.9677 | 2.3695 | 0.0072 | 0.0078 | 5.6174 |
| NSC 663284 | SUM149PT | -3.7773 | 0.9808 | -5.6728 | -5.6714 | -5.7412 | 2.9745 | 0.0053 | 0.0053 | 5.9823 |
| NSC 663284 | SUM159PT | -3.7773 | 0.9419 | -5.7833 | -5.7829 | -5.7996 | 3.5265 | 0.0000 | 0.0000 | 5.6696 |
| NSC 663284 | SUM185PE | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| NSC 663284 | SUM225CWN | -3.7773 | 0.9629 | -5.3948 | -5.3946 | -5.6456 | 1.9455 | 0.0000 | 0.0008 | 6.2917 |
| NSC 663284 | SUM229PE | -3.7773 | 0.9654 | -5.3373 | -5.3352 | -5.3879 | 4.0000 | 0.0092 | 0.0092 | 6.2323 |