Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| CGC-11047 | 184A1 | -2.3010 | 0.8747 | -3.3727 | -3.3723 | -4.2763 | 2.1165 | 0.0010 | 0.0079 | 6.2622 |
| CGC-11047 | MCF12A | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| CGC-11047 | MX1 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| CGC-11047 | T47DKBLUC | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| CGC-11047 | 600MPE | -2.3010 | 0.8404 | -2.7416 | -2.7416 | -3.5947 | 1.6266 | 0.0000 | 0.2296 | 7.1932 |
| CGC-11047 | HCC2185 | -2.3010 | 0.7274 | -2.8409 | -2.8409 | -4.3514 | 1.3850 | 0.0000 | 0.1625 | 6.8356 |
| CGC-11047 | HCC3153 | -2.3010 | 0.9469 | -4.0550 | -4.0547 | -5.2434 | 0.4595 | 0.0000 | 0.1352 | 5.7945 |
| CGC-11047 | LY2 | -2.3010 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 6.9649 |
| CGC-11047 | ZR75B | -2.3010 | 0.8085 | -2.9384 | -2.9384 | -3.5582 | 1.0595 | 0.0000 | 0.2371 | 7.1828 |
| CGC-11144 | MCF7 | -3.1500 | 0.9721 | -5.5230 | -5.5234 | -6.3001 | 0.6162 | 0.0000 | 0.0333 | 5.0893 |
| CGC-11144 | SK-BR-3 | -3.1500 | 0.9541 | -4.9665 | -4.9664 | -5.3509 | 0.7282 | 0.0000 | 0.0463 | 5.7521 |
| CGC-11144 | MDA-MB-231 | -3.1500 | 0.8848 | -5.1760 | -5.1765 | -5.2321 | 0.7870 | 0.0000 | 0.0143 | 5.7724 |
| CGC-11144 | AU565 | -3.1500 | 0.9771 | -6.1935 | -6.1874 | -6.3518 | 1.3880 | 0.0097 | 0.0102 | 4.1883 |
| CGC-11144 | BT-20 | -3.1500 | 0.9752 | -6.3740 | -6.3692 | -6.6631 | 2.2130 | 0.0131 | 0.0131 | 4.1276 |
| CGC-11144 | BT-474 | -3.1500 | 0.9671 | -5.3305 | -5.3304 | -5.9815 | 0.8923 | 0.0000 | 0.0112 | 5.4047 |
| CGC-11144 | BT-483 | -3.1500 | 0.9796 | -5.6230 | -5.6166 | -6.2077 | 1.2990 | 0.0089 | 0.0095 | 4.8509 |
| CGC-11144 | BT-549 | -3.1500 | 0.9470 | -6.4240 | -6.4207 | -6.5607 | 0.7818 | 0.0033 | 0.0071 | 4.0014 |
| CGC-11144 | CAMA-1 | -3.1500 | 0.9865 | -6.0860 | -6.0621 | -6.5516 | 0.9931 | 0.0269 | 0.0280 | 4.3835 |
| CGC-11144 | HCC1143 | -3.1500 | 0.9895 | -6.7860 | -6.7811 | -6.9109 | 1.8010 | 0.0109 | 0.0109 | 3.3702 |
| CGC-11144 | HCC1395 | -3.1500 | 0.9646 | -5.6465 | -5.6464 | -6.3158 | 0.6910 | 0.0000 | 0.0188 | 4.7939 |
| CGC-11144 | HCC1419 | -3.1500 | 0.8842 | -6.1945 | -6.1857 | -6.5339 | 2.0770 | 0.0204 | 0.0204 | 4.0175 |
| CGC-11144 | HCC1428 | -3.1500 | 0.9957 | -6.1675 | -6.1629 | -6.4617 | 1.9715 | 0.0100 | 0.0100 | 4.2252 |
| CGC-11144 | HCC1569 | -3.1500 | 0.9046 | -5.8990 | -5.8988 | -6.3397 | 0.4704 | 0.0000 | 0.0485 | 6.6435 |
| CGC-11144 | HCC1806 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| CGC-11144 | HCC1937 | -3.1500 | 0.9900 | -6.6190 | -6.6173 | -6.7567 | 2.0810 | 0.0050 | 0.0050 | 6.5606 |