Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| CGC-11144 | HCC1954 | -3.1500 | 0.9450 | -6.5110 | -6.5077 | -6.6591 | 2.6450 | 0.0068 | 0.0068 | 3.4764 |
| CGC-11144 | HCC202 | -3.1500 | 0.9905 | -6.2350 | -6.2345 | -6.4570 | 4.0000 | 0.0042 | 0.0042 | 4.1523 |
| CGC-11144 | HCC38 | -3.1500 | 0.9888 | -6.7130 | -6.7121 | -6.8404 | 2.3370 | 0.0077 | 0.0077 | 3.4151 |
| CGC-11144 | HCC70 | -3.1500 | 0.9768 | -6.3890 | -6.3820 | -6.5904 | 1.9810 | 0.0151 | 0.0151 | 3.7473 |
| CGC-11144 | Hs 578T | -3.1500 | 0.9195 | -4.7950 | -4.7948 | -4.9516 | 1.6600 | 0.0000 | 0.0059 | 5.9958 |
| CGC-11144 | MB 157 | -3.1500 | 0.9869 | -6.3030 | -6.2968 | -6.3799 | 2.3270 | 0.0168 | 0.0168 | 4.2130 |
| CGC-11144 | MDA-MB-134-VI | -3.1500 | 0.9807 | -5.6050 | -5.6049 | -6.4374 | 0.7568 | 0.0000 | 0.0137 | 4.7685 |
| CGC-11144 | MDA-MB-157 | -3.1500 | 0.9911 | -6.7985 | -6.7957 | -7.0163 | 1.9580 | 0.0057 | 0.0057 | 3.3156 |
| CGC-11144 | MDA-MB-175-VII | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| CGC-11144 | MDA-MB-361 | -3.1500 | 0.9860 | -5.4570 | -5.4425 | -5.7701 | 1.5240 | 0.0248 | 0.0252 | 5.3168 |
| CGC-11144 | MDA-MB-436 | -3.1500 | 0.9599 | -6.2320 | -6.2034 | -6.4692 | 0.8518 | 0.0269 | 0.0292 | 4.2650 |
| CGC-11144 | MDA-MB-453 | -3.1500 | 0.9354 | -5.5400 | -5.5400 | -6.2566 | 0.4375 | 0.0000 | 0.0827 | 5.0358 |
| CGC-11144 | MDA-MB-468 | -3.1500 | 0.9747 | -6.1020 | -6.0854 | -6.3599 | 0.8229 | 0.0155 | 0.0192 | 4.4652 |
| CGC-11144 | T47D | -3.1500 | 0.9900 | -6.8050 | -6.8048 | -6.9870 | 2.1540 | 0.0000 | 0.0000 | 3.3268 |
| CGC-11144 | UACC-812 | -3.1500 | 0.9911 | -5.7680 | -5.7637 | -6.6812 | 0.7687 | 0.0041 | 0.0137 | 4.8019 |
| CGC-11144 | UACC-893 | -3.1500 | 0.9844 | -5.5275 | -5.5273 | -6.4248 | 0.6930 | 0.0000 | 0.0233 | 5.0683 |
| CGC-11144 | ZR-75-1 | -3.1500 | 0.9387 | -6.6530 | -4.4137 | -6.8405 | 1.5151 | 0.3120 | 0.3173 | 5.6189 |
| CGC-11144 | 184B5 | -3.1500 | 0.9953 | -5.4775 | -5.4718 | -5.6580 | 1.9745 | 0.0145 | 0.0146 | 5.2227 |
| CGC-11144 | HCC1187 | -3.1500 | 0.9743 | -5.7420 | -5.7424 | -6.1216 | 0.8242 | 0.0000 | 0.0138 | 4.9215 |
| CGC-11144 | MCF 10A | -3.1500 | 0.9374 | -5.7900 | -5.7897 | -5.8851 | 0.8967 | 0.0000 | 0.0058 | 5.0079 |
| CGC-11144 | MCF 10F | -3.1500 | 0.9678 | -5.8270 | -5.8263 | -5.9925 | 3.0130 | 0.0022 | 0.0022 | 4.9643 |
| CGC-11144 | SUM1315MO2 | -3.1500 | 0.9724 | -5.2820 | -5.2824 | -5.6838 | 1.2590 | 0.0000 | 0.0020 | 5.3740 |
| CGC-11144 | SUM149PT | -3.1500 | 0.9846 | -6.4820 | -6.4724 | -6.5808 | 1.7160 | 0.0184 | 0.0184 | 3.9177 |
| CGC-11144 | SUM159PT | -3.1500 | 0.9615 | -6.6100 | -6.5933 | -6.6719 | 0.9747 | 0.0181 | 0.0185 | 3.6906 |
| CGC-11144 | SUM185PE | -3.1500 | 0.9777 | -6.2200 | -6.1981 | -6.6771 | 1.2740 | 0.0309 | 0.0310 | 4.4827 |