Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| 5-DFUR | BT-483 | -2.3010 | 0.8857 | -1.9972 | -2.3010 | -4.0420 | 0.3377 | 0.0000 | 0.5556 | 7.6481 |
| 5-DFUR | BT-549 | -2.3010 | 0.9520 | -3.6210 | -3.4398 | -3.6133 | 0.7796 | 0.1390 | 0.2126 | 6.7109 |
| 5-DFUR | CAMA-1 | -2.3010 | 0.8488 | -3.4620 | -2.3010 | -3.7320 | 0.5666 | 0.4131 | 0.5189 | 7.2984 |
| 5-DFUR | HCC1143 | -2.3010 | 0.9197 | -4.0670 | -3.4280 | -4.1667 | 0.5179 | 0.2667 | 0.3463 | 6.8120 |
| 5-DFUR | HCC1395 | -2.3010 | 0.7875 | -2.6523 | -2.6523 | -3.5298 | 0.4210 | 0.0000 | 0.4078 | 7.1221 |
| 5-DFUR | HCC1419 | -2.3010 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.2259 |
| 5-DFUR | HCC1428 | -2.3010 | 0.9488 | -3.0800 | -3.0800 | -4.1241 | 0.5954 | 0.0000 | 0.2607 | 7.0103 |
| 5-DFUR | HCC1569 | -2.3010 | 0.9182 | -2.3624 | -2.5871 | -3.3387 | 0.3978 | 0.0027 | 0.4755 | 7.5293 |
| 5-DFUR | HCC1806 | -2.3010 | 0.9081 | -3.6850 | -3.6848 | -4.0833 | 0.4124 | 0.0000 | 0.2118 | 6.0697 |
| 5-DFUR | HCC1937 | -2.3010 | 0.9107 | -3.3200 | -2.6722 | -3.3787 | 0.8422 | 0.3577 | 0.4359 | 7.8002 |
| 5-DFUR | HCC1954 | -2.3010 | 0.9434 | -3.6450 | -3.5227 | -4.0170 | 0.5862 | 0.0763 | 0.2057 | 6.7630 |
| 5-DFUR | HCC202 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| 5-DFUR | HCC38 | -2.3010 | 0.9100 | -3.5578 | -3.3567 | -3.8397 | 0.5512 | 0.0979 | 0.2687 | 6.7165 |
| 5-DFUR | HCC70 | -2.3010 | 0.8809 | -2.8128 | -2.8128 | -3.6082 | 0.4174 | 0.0000 | 0.3784 | 7.2054 |
| 5-DFUR | Hs 578T | -2.3010 | 0.9597 | -3.2156 | -3.2157 | -3.5345 | 0.5663 | 0.0000 | 0.2328 | 6.8530 |
| 5-DFUR | MB 157 | -2.3010 | 0.9743 | -5.1030 | -4.9798 | -5.0609 | 3.9990 | 0.3398 | 0.3398 | 6.0249 |
| 5-DFUR | MDA-MB-134-VI | -2.3010 | 0.8293 | -2.3420 | -2.3116 | -3.2528 | 0.5893 | 0.0878 | 0.5306 | 7.9144 |
| 5-DFUR | MDA-MB-157 | -2.3010 | 0.8748 | -3.8560 | -2.3010 | -3.9345 | 0.4172 | 0.3890 | 0.5011 | 7.2360 |
| 5-DFUR | MDA-MB-175-VII | -2.3010 | 0.8271 | -4.2280 | -2.3010 | -6.3090 | 1.8078 | 0.2936 | 0.5540 | 7.1780 |
| 5-DFUR | MDA-MB-361 | -2.3010 | 0.8234 | -2.5150 | -2.3010 | -3.2888 | 1.3577 | 0.3602 | 0.6777 | 8.1986 |
| 5-DFUR | MDA-MB-436 | -2.3010 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 7.8871 |
| 5-DFUR | MDA-MB-453 | -2.3010 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 6.8776 |
| 5-DFUR | MDA-MB-468 | -2.3010 | 0.9117 | -3.0204 | -2.9422 | -3.2296 | 0.7345 | 0.0620 | 0.2763 | 7.3019 |
| 5-DFUR | T47D | -2.3010 | 0.8637 | -2.7342 | -2.7342 | -3.4262 | 0.3806 | 0.0000 | 0.4062 | 7.1498 |
| 5-DFUR | UACC-812 | -2.3010 | 0.8253 | -4.5010 | -2.8125 | -4.7259 | 1.5473 | 0.4570 | 0.5146 | 6.9509 |