Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| TCS 2312 | MCF7 | -4.4776 | 0.9777 | -5.7676 | -5.7677 | -6.0070 | 1.4600 | 0.0000 | 0.0129 | 6.5153 |
| TCS 2312 | SK-BR-3 | -4.4776 | 0.9337 | -5.9966 | -5.9970 | -6.2957 | 1.3310 | 0.0000 | 0.0094 | 6.1078 |
| TCS 2312 | MDA-MB-231 | -4.4776 | 0.8250 | -6.0666 | -6.0477 | -6.0895 | 3.9980 | 0.0787 | 0.0787 | 7.3576 |
| TCS 2312 | AU565 | -4.4776 | 0.9759 | -6.4866 | -6.4847 | -6.5654 | 3.9990 | 0.0109 | 0.0109 | 5.8846 |
| TCS 2312 | BT-20 | -4.4776 | 0.9518 | -5.6116 | -5.5580 | -5.7904 | 2.0580 | 0.1128 | 0.1172 | 6.9715 |
| TCS 2312 | BT-474 | -4.4776 | 0.8811 | -5.9406 | -5.5397 | -6.2470 | 1.1490 | 0.3070 | 0.3295 | 7.0540 |
| TCS 2312 | BT-483 | -4.4776 | 0.9387 | -5.8331 | -4.9545 | -6.2125 | 1.4100 | 0.4661 | 0.4781 | 7.6928 |
| TCS 2312 | BT-549 | -4.4776 | 0.9728 | -6.3076 | -6.2951 | -6.3431 | 2.3960 | 0.0325 | 0.0326 | 5.9454 |
| TCS 2312 | CAMA-1 | -4.4776 | 0.9568 | -5.7756 | -5.7308 | -6.1203 | 1.3850 | 0.0641 | 0.0818 | 6.5700 |
| TCS 2312 | HCC1143 | -4.4776 | 0.9582 | -6.4956 | -6.4399 | -6.5542 | 2.4380 | 0.1341 | 0.1341 | 6.0207 |
| TCS 2312 | HCC1395 | -4.4776 | 0.9530 | -6.5321 | -6.4950 | -7.0285 | 0.8618 | 0.0321 | 0.0486 | 5.5994 |
| TCS 2312 | HCC1419 | -4.4776 | 0.8778 | -5.7316 | -5.5173 | -5.9623 | 1.8130 | 0.2953 | 0.2990 | 7.1514 |
| TCS 2312 | HCC1428 | -4.4776 | 0.9819 | -5.8671 | -5.8401 | -6.1520 | 1.8705 | 0.0544 | 0.0568 | 6.5391 |
| TCS 2312 | HCC1569 | -4.4776 | 0.9706 | -6.2511 | -6.1864 | -6.3416 | 3.1770 | 0.1869 | 0.1869 | 6.4763 |
| TCS 2312 | HCC1806 | -4.4776 | 0.9584 | -6.1976 | -6.1902 | -6.2588 | 2.8340 | 0.0233 | 0.0233 | 5.8777 |
| TCS 2312 | HCC1937 | -4.4776 | 0.9475 | -6.2886 | -6.1806 | -6.5699 | 1.1010 | 0.1201 | 0.1289 | 6.1198 |
| TCS 2312 | HCC1954 | -4.4776 | 0.9016 | -5.5376 | -5.4278 | -5.5449 | 3.5230 | 0.2948 | 0.2949 | 7.9499 |
| TCS 2312 | HCC202 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| TCS 2312 | HCC38 | -4.4776 | 0.9816 | -6.9366 | -6.9263 | -7.0217 | 2.7685 | 0.0319 | 0.0319 | 5.0339 |
| TCS 2312 | HCC70 | -4.4776 | 0.9824 | -6.4221 | -6.4147 | -6.5803 | 2.7325 | 0.0241 | 0.0241 | 5.7942 |
| TCS 2312 | Hs 578T | -4.4776 | 0.9857 | -6.0736 | -6.0439 | -6.1500 | 1.6190 | 0.0528 | 0.0552 | 6.2493 |
| TCS 2312 | MB 157 | -4.4776 | 0.9897 | -6.3886 | -6.3458 | -6.4006 | 4.0000 | 0.1633 | 0.1633 | 6.3309 |
| TCS 2312 | MDA-MB-134-VI | -4.4776 | 0.9188 | -5.6986 | -5.5117 | -5.7896 | 2.5390 | 0.3777 | 0.3863 | 7.6140 |
| TCS 2312 | MDA-MB-157 | -4.4776 | 0.9847 | -6.7216 | -6.7088 | -6.8055 | 4.0000 | 0.0542 | 0.0542 | 5.6916 |
| TCS 2312 | MDA-MB-175-VII | -4.4776 | 0.8619 | -5.6106 | -4.4776 | -5.9556 | 0.9789 | 0.3623 | 0.5772 | 7.8359 |