Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| TCS 2312 | MDA-MB-361 | -4.4776 | 0.9730 | -6.2196 | -6.1321 | -6.5555 | 1.6670 | 0.1403 | 0.1415 | 6.7188 |
| TCS 2312 | MDA-MB-436 | -4.4776 | 0.9429 | -6.3306 | -6.2105 | -6.4402 | 2.9880 | 0.2816 | 0.2816 | 6.9652 |
| TCS 2312 | MDA-MB-453 | -4.4776 | 0.9886 | -6.0106 | -6.0097 | -6.3186 | 1.3850 | 0.0007 | 0.0082 | 6.1418 |
| TCS 2312 | MDA-MB-468 | -4.4776 | 0.9842 | -6.1956 | -6.1897 | -6.2343 | 4.0000 | 0.0255 | 0.0255 | 6.0150 |
| TCS 2312 | T47D | -4.4776 | 0.9580 | -5.9286 | -5.8155 | -5.9240 | 3.9970 | 0.3241 | 0.3241 | 7.1817 |
| TCS 2312 | UACC-812 | -4.4776 | 0.9581 | -5.7536 | -5.6759 | -6.0233 | 1.4460 | 0.2562 | 0.2683 | 7.0031 |
| TCS 2312 | UACC-893 | -4.4776 | 0.9780 | -5.8956 | -5.8828 | -6.2477 | 2.2180 | 0.0323 | 0.0330 | 6.3885 |
| TCS 2312 | ZR-75-1 | -4.4776 | 0.8659 | -5.6386 | -5.5092 | -6.1816 | 0.9953 | 0.1520 | 0.2913 | 6.9206 |
| TCS 2312 | 184B5 | -4.4776 | 0.9653 | -6.2456 | -6.1818 | -6.3464 | 2.2300 | 0.1387 | 0.1388 | 6.5019 |
| TCS 2312 | HCC1187 | -4.4776 | 0.9788 | -5.9906 | -5.9797 | -6.1009 | 3.3115 | 0.0380 | 0.0380 | 6.3255 |
| TCS 2312 | MCF 10A | -4.4776 | 0.9646 | -5.9026 | -5.8971 | -5.9255 | 4.0000 | 0.0235 | 0.0235 | 6.6063 |
| TCS 2312 | MCF 10F | -4.4776 | 0.9578 | -5.6206 | -5.6036 | -5.6971 | 2.7820 | 0.0511 | 0.0517 | 7.1830 |
| TCS 2312 | SUM1315MO2 | -4.4776 | 0.9728 | -6.1096 | -6.1001 | -6.5146 | 1.3735 | 0.0148 | 0.0222 | 6.1894 |
| TCS 2312 | SUM149PT | -4.4776 | 0.9815 | -6.5496 | -6.5404 | -6.6528 | 1.9745 | 0.0200 | 0.0203 | 5.7115 |
| TCS 2312 | SUM159PT | -4.4776 | 0.9371 | -6.2601 | -6.2497 | -6.2669 | 3.8625 | 0.0454 | 0.0454 | 6.1107 |
| TCS 2312 | SUM185PE | -4.4776 | 0.8544 | -6.4236 | -6.2384 | -6.8515 | 0.9828 | 0.1713 | 0.1813 | 6.5487 |
| TCS 2312 | SUM225CWN | -4.4776 | 0.8897 | -5.8876 | -5.7337 | -6.1060 | 1.6380 | 0.2164 | 0.2243 | 7.2159 |
| TCS 2312 | SUM229PE | -4.4776 | 0.8955 | -5.9426 | -5.7883 | -5.9245 | 2.1750 | 0.2686 | 0.2691 | 7.2144 |
| TCS 2312 | SUM52PE | -4.4776 | 0.9618 | -6.3121 | -6.2181 | -6.4374 | 2.0240 | 0.1728 | 0.1729 | 6.4488 |
| TCS 2312 | 184A1 | -4.4776 | 0.9449 | -6.2116 | -6.1148 | -6.2991 | 2.3240 | 0.2026 | 0.2027 | 6.7051 |
| TCS 2312 | MCF12A | -4.4776 | 0.9764 | -6.0606 | -5.9924 | -6.1961 | 1.4460 | 0.1040 | 0.1091 | 6.5078 |
| TCS 2312 | MX1 | -4.4776 | 0.9835 | -6.3416 | -6.3361 | -6.7392 | 2.7740 | 0.0199 | 0.0199 | 5.9962 |
| TCS 2312 | T47DKBLUC | -4.4776 | 0.9797 | -5.5356 | -5.2637 | -5.5326 | 3.9950 | 0.4590 | 0.4590 | 7.8743 |
| TCS 2312 | 600MPE | -4.4776 | 0.9624 | -5.9916 | -5.9100 | -6.0910 | 2.9930 | 0.2143 | 0.2143 | 6.8374 |
| TCS 2312 | HCC2185 | -4.4776 | 0.8455 | -5.7356 | -4.9200 | -5.8538 | 2.9095 | 0.4194 | 0.4221 | 7.6084 |