LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Taxol | 180703_BG_11 | 2317 | 0.6493 | 728 | 1249 | 13 | 5 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_6 | 1977 | 0.4604 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.42861 | 0.1383 |
| Taxol | 180703_BG_12 | 3131 | 0.4436 | 381 | 1177 | 12 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 1558 | 0.3323 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.30047 | 0.2282 |
| Taxol | 180703_BG_12 | 2585 | 0.5196 | 421 | 1141 | 3 | 14 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 1562 | 0.3767 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.34486 | 0.1702 |
| Taxol | 180703_BG_12 | 2901 | 0.4723 | 457 | 1129 | 14 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_9 | 1586 | 0.3535 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.32167 | 0.2048 |
| Taxol | 180703_BG_10 | 2069 | 0.6300 | 493 | 1121 | 3 | 9 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_1 | 1614 | 0.4382 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.40643 | 0.1062 |
| Taxol | 180703_BG_11 | 1739 | 0.7248 | 677 | 1074 | 5 | 16 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_4 | 1751 | 0.5017 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.46992 | 0.0587 |
| Taxol | 180703_BG_11 | 2233 | 0.5700 | 467 | 1072 | 11 | 11 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_5 | 1539 | 0.4080 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.37621 | 0.1277 |
| Taxol | 180703_BG_10 | 1898 | 0.5739 | 287 | 967 | 4 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_3 | 1254 | 0.3978 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.36604 | 0.0823 |
| Taxol | 180703_BG_11 | 10048 | 0.1286 | 377 | 964 | 9 | 9 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_4 | 1341 | 0.1177 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.08595 | 0.6490 |
| Taxol | 180703_BG_10 | 1845 | 0.5696 | 290 | 926 | 4 | 16 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_2 | 1216 | 0.3973 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.36546 | 0.0746 |
| Vorinostat | 180703_BG_11 | 22204 | 0.0466 | 140 | 901 | 9 | 18 | Vorinostat | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_5 | 1041 | 0.0448 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.01298 | 1.0148 |
| Taxol | 180703_BG_10 | 7939 | 0.1506 | 373 | 879 | 5 | 21 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_1 | 1252 | 0.1362 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.10442 | 0.5537 |
| Neratinib | 180703_BG_12 | 21766 | 0.0430 | 74 | 866 | 9 | 12 | Neratinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 940 | 0.0414 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00960 | 1.0047 |
| Alpelisib | 180703_BG_12 | 22357 | 0.0406 | 76 | 834 | 9 | 15 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_9 | 910 | 0.0391 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00731 | 1.0183 |
| Vorinostat | 180703_BG_12 | 21761 | 0.0411 | 65 | 833 | 5 | 12 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_7 | 898 | 0.0396 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00783 | 1.0046 |
| Taxol | 180703_BG_10 | 7458 | 0.1455 | 296 | 832 | 7 | 16 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_2 | 1128 | 0.1314 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.09958 | 0.5294 |
| Vorinostat | 180703_BG_12 | 22083 | 0.0411 | 80 | 831 | 3 | 18 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 911 | 0.0396 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00782 | 1.0120 |
| Neratinib | 180703_BG_11 | 21921 | 0.0437 | 137 | 828 | 11 | 4 | Neratinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_6 | 965 | 0.0422 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.01037 | 1.0083 |
| Vorinostat | 180703_BG_12 | 21586 | 0.0416 | 82 | 819 | 3 | 16 | Vorinostat | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_7 | 901 | 0.0401 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00827 | 1.0005 |
| Taxol | 180703_BG_10 | 8562 | 0.1216 | 259 | 814 | 7 | 22 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_3 | 1073 | 0.1114 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.07957 | 0.5837 |
| Vorinostat | 180703_BG_10 | 21962 | 0.0385 | 38 | 808 | 13 | 11 | Vorinostat | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_3 | 846 | 0.0371 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00529 | 1.0092 |
| Vorinostat | 180703_BG_12 | 21825 | 0.0399 | 68 | 805 | 13 | 18 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_9 | 873 | 0.0385 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00666 | 1.0061 |
| Palbociclib | 180703_BG_12 | 21701 | 0.0403 | 73 | 804 | 13 | 6 | Palbociclib | 0.001081167 | treatment | 72 | 3 | MCF10A-GM_9 | 877 | 0.0388 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00704 | 1.0032 |
| Taxol | 180703_BG_11 | 10101 | 0.0981 | 217 | 795 | 12 | 12 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_5 | 1012 | 0.0911 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.05927 | 0.6512 |
| Vorinostat | 180703_BG_12 | 22260 | 0.0388 | 76 | 791 | 7 | 17 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_8 | 867 | 0.0375 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00569 | 1.0161 |