LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Palbociclib | 180703_BG_10 | 7774 | 0.0109 | 39 | 46 | 12 | 13 | Palbociclib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_3 | 85 | 0.0108 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.02098 | 0.5455 |
| Palbociclib | 180703_BG_10 | 7560 | 0.0111 | 37 | 47 | 4 | 21 | Palbociclib | 0.332666627 | treatment | 72 | 3 | MCF10A-GM_2 | 84 | 0.0110 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.02081 | 0.5347 |
| Trametinib | 180703_BG_10 | 14550 | 0.0125 | 57 | 125 | 10 | 19 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_2 | 182 | 0.0124 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01945 | 0.8107 |
| Neratinib | 180703_BG_10 | 14443 | 0.0129 | 30 | 157 | 11 | 14 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_1 | 187 | 0.0128 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01902 | 0.8074 |
| Neratinib | 180703_BG_10 | 14578 | 0.0129 | 38 | 151 | 14 | 18 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_3 | 189 | 0.0128 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01900 | 0.8116 |
| Trametinib | 180703_BG_12 | 11390 | 0.0132 | 48 | 103 | 14 | 12 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_9 | 151 | 0.0131 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01872 | 0.7021 |
| Trametinib | 180703_BG_10 | 14205 | 0.0133 | 46 | 144 | 6 | 8 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_1 | 190 | 0.0132 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01860 | 0.7998 |
| Alpelisib | 180703_BG_10 | 10077 | 0.0135 | 44 | 93 | 8 | 7 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_2 | 137 | 0.0134 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01839 | 0.6502 |
| Etoposide | 180703_BG_10 | 13559 | 0.0136 | 48 | 137 | 9 | 13 | Etoposide | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_2 | 185 | 0.0135 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01834 | 0.7787 |
| Alpelisib | 180703_BG_10 | 7647 | 0.0137 | 32 | 73 | 12 | 19 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_3 | 105 | 0.0135 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01825 | 0.5391 |
| Alpelisib | 180703_BG_10 | 14895 | 0.0138 | 47 | 159 | 12 | 11 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_3 | 206 | 0.0136 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01816 | 0.8215 |
| Trametinib | 180703_BG_10 | 9284 | 0.0140 | 50 | 81 | 12 | 21 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_2 | 131 | 0.0139 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01789 | 0.6164 |
| Palbociclib | 180703_BG_10 | 17887 | 0.0142 | 38 | 216 | 9 | 7 | Palbociclib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_1 | 254 | 0.0140 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01780 | 0.9077 |
| Dasatinib | 180703_BG_10 | 18337 | 0.0142 | 51 | 210 | 12 | 18 | Dasatinib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_3 | 261 | 0.0140 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01777 | 0.9197 |
| Etoposide | 180703_BG_12 | 9932 | 0.0144 | 30 | 113 | 10 | 11 | Etoposide | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_9 | 143 | 0.0142 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01761 | 0.6442 |
| Alpelisib | 180703_BG_10 | 16726 | 0.0145 | 42 | 201 | 5 | 20 | Alpelisib | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_1 | 243 | 0.0143 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01748 | 0.8756 |
| Trametinib | 180703_BG_12 | 16500 | 0.0145 | 44 | 196 | 12 | 14 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_9 | 240 | 0.0143 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01746 | 0.8692 |
| Trametinib | 180703_BG_12 | 10087 | 0.0145 | 35 | 112 | 10 | 9 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 147 | 0.0144 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01744 | 0.6506 |
| Dasatinib | 180703_BG_12 | 15475 | 0.0145 | 60 | 166 | 12 | 8 | Dasatinib | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_9 | 226 | 0.0144 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01741 | 0.8391 |
| Alpelisib | 180703_BG_10 | 17588 | 0.0147 | 40 | 219 | 12 | 6 | Alpelisib | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_3 | 259 | 0.0145 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01729 | 0.8996 |
| Palbociclib | 180703_BG_10 | 16274 | 0.0147 | 40 | 200 | 11 | 15 | Palbociclib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_3 | 240 | 0.0145 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01727 | 0.8627 |
| Neratinib | 180703_BG_12 | 14764 | 0.0149 | 46 | 174 | 4 | 6 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_7 | 220 | 0.0147 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01712 | 0.8174 |
| Palbociclib | 180703_BG_10 | 14713 | 0.0151 | 35 | 187 | 14 | 11 | Palbociclib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_3 | 222 | 0.0149 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01693 | 0.8158 |
| Alpelisib | 180703_BG_10 | 8407 | 0.0152 | 39 | 89 | 8 | 17 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_1 | 128 | 0.0150 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01680 | 0.5764 |
| Dasatinib | 180703_BG_10 | 17271 | 0.0152 | 49 | 214 | 11 | 16 | Dasatinib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_2 | 263 | 0.0150 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01680 | 0.8909 |