LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)

Data Columns

  • 24 Data Columns
Name Description Display Name Data Type Unit Precision Readout Type Replicate Comments
smallMolecule
Small molecule perturbagen
Small Molecule small_molecule
barcode
Unique identifier for a given 384/96 well plate
barcode Text
well
Name of the well on the 384/96 well plate
well Text
cellCount
Number of cells quantified as live in a given well
cell_count Numeric 0
fracDead
Fraction of cells quantified as dead in a given well
frac_dead Numeric 4
corpseCount
Number of cells quantified as dead (Hoesht negative, LDR positive cells) in a given well
corpse_count Numeric 0
cellCountDead
Number of cells quantified as dead (Hoescnt positive, LDR positive) in a given well
cell_count_dead Numeric 0
row
Name of row for a given well on the 384/96 well plate
row Numeric 0
column
Column number for a given well on the 384/96 well plate
column Numeric 0
agent
Name of the drug or treatment in a given well
agent Text
concentration
Concentration of the drug in micromolar in a given well
concentration Text
role
Role of the drug i.e treatment, positive control or negative control
role Text
timepoint
Duration of time (in hours) fo which the cell was treated prior to measurement
timepoint Numeric 0
replicate
If a condition is repeated 2 or more times on a single plate, a unique replicate number is assigned (1, 2, or 3) to each replicate condition
replicate Numeric 0
cellLine
Name of the cell line in a given well
cell_line Text
deadCount
cell_count__dead + corpse_count
dead_count Numeric 0
fractionDead
Fraction of cells quantified as dead in a given well
fraction_dead Numeric 4
cellCountTime0
Mean number of cells quantified as alive in time=0 control plate
cell_count__time0 Numeric 1
deadCountTime0
Mean number of cells quantified as dead in time=0 control plate
dead_count__time0 Numeric 1
cellCountCtrl
Mean number of cells quantified as alive in DMSO control (t=72 hrs)
cell_count__ctrl Numeric 0
deadCountCtrl
Mean number of cells quantified as dead in DMSO control wells (t=72 hrs)
dead_count__ctrl Numeric 1
fractionDeadCtrl
Mean fraction of cells quatified as dead in DMSO control wells
fraction_dead__ctrl Numeric 4
increaseFractionDead
Increase in the fraction of dead cells relative to time=0 control
increase_fraction_dead Numeric 5
gRvalue
Growth corrected dose response for a given well/condition
GRvalue Numeric 4
  • 24 Data Columns