LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neratinib | 180614_BG_03 | 17919 | 0.0179 | 46 | 275 | 13 | 3 | Neratinib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_6 | 321 | 0.0176 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00240 | 1.0233 |
| Palbociclib | 180614_BG_02 | 11181 | 0.0199 | 58 | 166 | 6 | 3 | Palbociclib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 224 | 0.0196 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00036 | 0.8114 |
| Etoposide | 180614_BG_03 | 4519 | 0.0341 | 60 | 96 | 8 | 3 | Etoposide | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_4 | 156 | 0.0334 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01337 | 0.4645 |
| Etoposide | 180614_BG_04 | 1122 | 0.1804 | 186 | 50 | 4 | 3 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_7 | 236 | 0.1738 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.15379 | 0.0561 |
| Taxol | 180614_BG_02 | 480 | 0.9858 | 295 | 469 | 8 | 3 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_3 | 764 | 0.6141 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.59415 | -0.1346 |
| Palbociclib | 180614_BG_03 | 15770 | 0.0169 | 73 | 195 | 6 | 3 | Palbociclib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_4 | 268 | 0.0167 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00329 | 0.9636 |
| Etoposide | 180614_BG_03 | 17346 | 0.0193 | 43 | 292 | 10 | 3 | Etoposide | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_4 | 335 | 0.0189 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00105 | 1.0080 |
| Etoposide | 180614_BG_03 | 15513 | 0.0207 | 75 | 247 | 4 | 3 | Etoposide | 0.00998 | treatment | 72 | 1 | MCF10A-GM_4 | 322 | 0.0203 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00034 | 0.9560 |
| Alpelisib | 180614_BG_02 | 12302 | 0.0143 | 23 | 153 | 5 | 3 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_1 | 176 | 0.0141 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00589 | 0.8524 |
| Etoposide | 180614_BG_04 | 1073 | 0.2452 | 171 | 134 | 3 | 3 | Etoposide | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_7 | 305 | 0.2213 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.20134 | 0.0451 |
| Neratinib | 180614_BG_02 | 1544 | 0.0852 | 41 | 94 | 10 | 3 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_1 | 135 | 0.0804 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.06041 | 0.1383 |
| Neratinib | 180614_BG_04 | 2730 | 0.0411 | 42 | 72 | 7 | 3 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_8 | 114 | 0.0401 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.02009 | 0.3012 |
| Dasatinib | 180614_BG_02 | 4298 | 0.0778 | 47 | 291 | 11 | 3 | Dasatinib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_3 | 338 | 0.0729 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.05291 | 0.4474 |
| Dasatinib | 180614_BG_04 | 17045 | 0.0174 | 96 | 202 | 9 | 3 | Dasatinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_8 | 298 | 0.0172 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00281 | 0.9997 |
| Dasatinib | 180614_BG_02 | 15955 | 0.0207 | 50 | 281 | 13 | 3 | Dasatinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_3 | 331 | 0.0203 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00033 | 0.9690 |
| Dasatinib | 180614_BG_02 | 1400 | 0.2763 | 55 | 347 | 12 | 3 | Dasatinib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_2 | 402 | 0.2231 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.20309 | 0.1125 |
| Alpelisib | 180614_BG_02 | 16888 | 0.0194 | 31 | 298 | 9 | 3 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_2 | 329 | 0.0191 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00089 | 0.9954 |
| Dasatinib | 180614_BG_02 | 17360 | 0.0204 | 53 | 303 | 3 | 3 | Dasatinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 356 | 0.0201 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00010 | 1.0084 |
| Alpelisib | 180614_BG_03 | 14508 | 0.0222 | 114 | 211 | 3 | 3 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_4 | 325 | 0.0219 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00192 | 0.9255 |
| Alpelisib | 180614_BG_02 | 16699 | 0.0169 | 46 | 237 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_3 | 283 | 0.0167 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00333 | 0.9901 |
| Alpelisib | 180614_BG_04 | 15464 | 0.0170 | 49 | 215 | 5 | 3 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_8 | 264 | 0.0168 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00321 | 0.9546 |
| Dasatinib | 180614_BG_04 | 10039 | 0.0320 | 151 | 175 | 6 | 3 | Dasatinib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_8 | 326 | 0.0315 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01146 | 0.7662 |
| Alpelisib | 180614_BG_03 | 16992 | 0.0167 | 38 | 247 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_6 | 285 | 0.0165 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00350 | 0.9983 |
| Palbociclib | 180614_BG_04 | 14208 | 0.0234 | 132 | 204 | 11 | 3 | Palbociclib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_9 | 336 | 0.0231 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00311 | 0.9161 |
| Palbociclib | 180614_BG_03 | 13012 | 0.0166 | 79 | 138 | 5 | 3 | Palbociclib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_6 | 217 | 0.0164 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00359 | 0.8770 |