LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vorinostat | 180703_BG_10 | 22679 | 0.0345 | 62 | 723 | 5 | 13 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_1 | 785 | 0.0335 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00166 | 1.0256 |
| Palbociclib | 180703_BG_10 | 22434 | 0.0331 | 41 | 704 | 13 | 10 | Palbociclib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_3 | 745 | 0.0321 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00034 | 1.0201 |
| Vorinostat | 180703_BG_12 | 22383 | 0.0365 | 63 | 756 | 8 | 12 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 819 | 0.0353 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00350 | 1.0189 |
| Alpelisib | 180703_BG_12 | 22357 | 0.0406 | 76 | 834 | 9 | 15 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_9 | 910 | 0.0391 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00731 | 1.0183 |
| Vorinostat | 180703_BG_12 | 22260 | 0.0388 | 76 | 791 | 7 | 17 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_8 | 867 | 0.0375 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00569 | 1.0161 |
| Taxol | 180703_BG_11 | 22225 | 0.0365 | 127 | 689 | 13 | 17 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_6 | 816 | 0.0354 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00362 | 1.0153 |
| Vorinostat | 180703_BG_11 | 22204 | 0.0466 | 140 | 901 | 9 | 18 | Vorinostat | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_5 | 1041 | 0.0448 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.01298 | 1.0148 |
| Etoposide | 180703_BG_12 | 22184 | 0.0307 | 72 | 611 | 11 | 4 | Etoposide | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_7 | 683 | 0.0299 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00193 | 1.0144 |
| Vorinostat | 180703_BG_11 | 22169 | 0.0369 | 84 | 738 | 10 | 15 | Vorinostat | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_6 | 822 | 0.0358 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00395 | 1.0140 |
| Vorinostat | 180703_BG_12 | 22165 | 0.0374 | 85 | 748 | 5 | 21 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_7 | 833 | 0.0362 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00442 | 1.0139 |
| Neratinib | 180703_BG_11 | 22095 | 0.0341 | 115 | 643 | 8 | 7 | Neratinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_5 | 758 | 0.0332 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00137 | 1.0123 |
| Vorinostat | 180703_BG_12 | 22083 | 0.0411 | 80 | 831 | 3 | 18 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 911 | 0.0396 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00782 | 1.0120 |
| Vorinostat | 180703_BG_12 | 22077 | 0.0333 | 66 | 672 | 5 | 22 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 738 | 0.0323 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00055 | 1.0119 |
| Neratinib | 180703_BG_11 | 22054 | 0.0365 | 159 | 652 | 3 | 17 | Neratinib | 0.001081167 | treatment | 72 | 3 | MCF10A-GM_4 | 811 | 0.0355 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00367 | 1.0114 |
| Vorinostat | 180703_BG_11 | 22041 | 0.0390 | 159 | 706 | 9 | 3 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_6 | 865 | 0.0378 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00596 | 1.0111 |
| Neratinib | 180703_BG_11 | 22009 | 0.0353 | 117 | 664 | 14 | 10 | Neratinib | 0.001081167 | treatment | 72 | 3 | MCF10A-GM_5 | 781 | 0.0343 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00247 | 1.0103 |
| Vorinostat | 180703_BG_12 | 22009 | 0.0317 | 62 | 637 | 10 | 19 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_9 | 699 | 0.0308 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00102 | 1.0103 |
| Alpelisib | 180703_BG_12 | 22004 | 0.0359 | 56 | 737 | 14 | 10 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_9 | 793 | 0.0348 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00299 | 1.0102 |
| Vorinostat | 180703_BG_10 | 21996 | 0.0236 | 53 | 467 | 8 | 12 | Vorinostat | 0.00998 | treatment | 72 | 3 | MCF10A-GM_1 | 520 | 0.0231 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00870 | 1.0100 |
| Neratinib | 180703_BG_11 | 21989 | 0.0434 | 195 | 768 | 3 | 9 | Neratinib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_4 | 963 | 0.0420 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.01016 | 1.0099 |
| Taxol | 180703_BG_10 | 21982 | 0.0284 | 39 | 587 | 12 | 5 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_2 | 626 | 0.0277 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00411 | 1.0097 |
| Vorinostat | 180703_BG_10 | 21962 | 0.0385 | 38 | 808 | 13 | 11 | Vorinostat | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_3 | 846 | 0.0371 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00529 | 1.0092 |
| Neratinib | 180703_BG_12 | 21955 | 0.0369 | 61 | 751 | 4 | 16 | Neratinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 812 | 0.0357 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00387 | 1.0091 |
| Alpelisib | 180703_BG_10 | 21952 | 0.0290 | 45 | 594 | 3 | 12 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_1 | 639 | 0.0283 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00351 | 1.0090 |
| Vorinostat | 180703_BG_12 | 21936 | 0.0326 | 45 | 672 | 12 | 18 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_9 | 717 | 0.0317 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00015 | 1.0086 |