LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 86.41 | 11.8 | Inf | Inf | 0.6220 | 0.6220 | 0.0000 | 0.3526 |
| MCF 10A-H2B-mCherry | Neratinib | 80.50 | 11.8 | Inf | Inf | -0.3030 | -0.3030 | 0.0000 | 0.4783 |
| MCF 10A-H2B-mCherry | Dasatinib | 86.41 | 11.8 | Inf | Inf | -0.9407 | -0.9407 | 0.0000 | 0.4348 |
| MCF 10A-H2B-mCherry | Neratinib | 84.44 | 11.8 | Inf | Inf | -0.2686 | -0.2686 | 0.0000 | 0.4519 |
| MCF 10A-H2B-mCherry | Dasatinib | 68.68 | 11.8 | Inf | Inf | -0.4111 | -0.4111 | 0.0000 | 0.2388 |
| MCF 10A-H2B-mCherry | Dasatinib | 88.39 | 11.8 | Inf | Inf | -0.9411 | -0.9411 | 0.0000 | 0.4784 |
| MCF 10A-H2B-mCherry | Dasatinib | 84.44 | 11.8 | Inf | Inf | -0.9625 | -0.9625 | 0.0000 | 0.4367 |
| MCF 10A-H2B-mCherry | Dasatinib | 80.50 | 11.8 | Inf | Inf | -0.9137 | -0.9137 | 0.0000 | 0.3813 |
| MCF 10A-H2B-mCherry | Neratinib | 82.47 | 11.8 | Inf | Inf | -0.2038 | -0.2038 | 0.0000 | 0.4483 |
| MCF 10A-H2B-mCherry | Alpelisib | 64.24 | 12.8 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | -0.0006 |
| MCF 10A-H2B-mCherry | Alpelisib | 14.50 | 11.8 | Inf | Inf | 0.5830 | 0.5830 | 0.0000 | 0.1656 |
| MCF 10A-H2B-mCherry | Alpelisib | 62.27 | 12.8 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | -0.0396 |
| MCF 10A-H2B-mCherry | Dasatinib | 82.47 | 11.8 | Inf | Inf | -0.9461 | -0.9461 | 0.0000 | 0.4375 |
| MCF 10A-H2B-mCherry | Dasatinib | 74.59 | 11.8 | Inf | Inf | -0.7935 | -0.7935 | 0.0000 | 0.3297 |
| MCF 10A-H2B-mCherry | Alpelisib | 16.47 | 11.8 | Inf | Inf | 0.5437 | 0.5437 | 0.0000 | 0.1861 |
| MCF 10A-H2B-mCherry | Alpelisib | 66.21 | 12.8 | Inf | Inf | 0.7208 | 0.7208 | 0.0000 | 0.0599 |
| MCF 10A-H2B-mCherry | Alpelisib | 47.98 | 11.8 | Inf | Inf | 0.8928 | 0.8928 | 0.0000 | 0.0043 |
| MCF 10A-H2B-mCherry | Alpelisib | 49.95 | 11.8 | Inf | Inf | 0.9252 | 0.9252 | 0.0000 | -0.0030 |
| MCF 10A-H2B-mCherry | Alpelisib | 51.92 | 11.8 | Inf | Inf | 0.9806 | 0.9806 | 0.0000 | 0.0026 |
| MCF 10A-H2B-mCherry | Alpelisib | 53.89 | 11.8 | Inf | Inf | 0.9884 | 0.9884 | 0.0000 | 0.0083 |
| MCF 10A-H2B-mCherry | Alpelisib | 56.36 | 12.8 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | 0.0012 |
| MCF 10A-H2B-mCherry | Alpelisib | 58.33 | 12.8 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | -0.0079 |
| MCF 10A-H2B-mCherry | Alpelisib | 60.30 | 12.8 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | -0.0098 |
| MCF 10A-H2B-mCherry | Vorinostat | 72.62 | 11.8 | Inf | Inf | 0.1396 | 0.1396 | 0.0000 | 0.1845 |
| MCF 10A-H2B-mCherry | Neratinib | 88.39 | 11.8 | Inf | Inf | 0.8099 | 0.8099 | 0.0000 | 0.3692 |