LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
---|---|---|---|---|---|---|---|---|---|
MCF 10A-H2B-mCherry | Dasatinib | 84.44 | 11.8 | Inf | Inf | -0.9625 | -0.9625 | 0.0000 | 0.4367 |
MCF 10A-H2B-mCherry | Dasatinib | 82.47 | 11.8 | Inf | Inf | -0.9461 | -0.9461 | 0.0000 | 0.4375 |
MCF 10A-H2B-mCherry | Taxol | 24.34 | 11.8 | 0.002 | 0.0046 | -0.9432 | -0.9101 | 1.2484 | 0.9442 |
MCF 10A-H2B-mCherry | Taxol | 20.40 | 11.8 | 0.0027 | 0.0057 | -0.9423 | -0.9486 | 1.4238 | 0.9269 |
MCF 10A-H2B-mCherry | Dasatinib | 88.39 | 11.8 | Inf | Inf | -0.9411 | -0.9411 | 0.0000 | 0.4784 |
MCF 10A-H2B-mCherry | Dasatinib | 86.41 | 11.8 | Inf | Inf | -0.9407 | -0.9407 | 0.0000 | 0.4348 |
MCF 10A-H2B-mCherry | Taxol | 22.37 | 11.8 | 0.0022 | 0.0052 | -0.9405 | -0.9510 | 1.3001 | 0.9473 |
MCF 10A-H2B-mCherry | Taxol | 16.47 | 11.8 | 0.0034 | 0.0083 | -0.9391 | -0.9437 | 1.3190 | 0.8401 |
MCF 10A-H2B-mCherry | Taxol | 18.43 | 11.8 | 0.003 | 0.0066 | -0.9335 | -0.9228 | 1.4098 | 0.8755 |
MCF 10A-H2B-mCherry | Dasatinib | 80.50 | 11.8 | Inf | Inf | -0.9137 | -0.9137 | 0.0000 | 0.3813 |
MCF 10A-H2B-mCherry | Taxol | 26.31 | 11.8 | 0.0016 | 0.0039 | -0.9101 | -0.9124 | 1.2276 | 0.9742 |
MCF 10A-H2B-mCherry | Taxol | 14.50 | 11.8 | 0.0054 | 0.0111 | -0.8917 | -0.8789 | 1.6037 | 0.7582 |
MCF 10A-H2B-mCherry | Dasatinib | 78.53 | 11.8 | Inf | Inf | -0.8878 | -0.9429 | 2.5000 | 0.3438 |
MCF 10A-H2B-mCherry | Taxol | 28.28 | 11.8 | 0.0013 | 0.003 | -0.8701 | -0.8390 | 1.2391 | 0.9847 |
MCF 10A-H2B-mCherry | Taxol | 32.22 | 11.8 | 0.001 | 0.0019 | -0.8341 | -0.7201 | 1.5049 | 0.9893 |
MCF 10A-H2B-mCherry | Taxol | 30.24 | 11.8 | 0.0011 | 0.0024 | -0.8135 | -0.8348 | 1.2978 | 1.0177 |
MCF 10A-H2B-mCherry | Dasatinib | 76.56 | 11.8 | Inf | Inf | -0.7949 | -0.9180 | 2.5000 | 0.3265 |
MCF 10A-H2B-mCherry | Dasatinib | 74.59 | 11.8 | Inf | Inf | -0.7935 | -0.7935 | 0.0000 | 0.3297 |
MCF 10A-H2B-mCherry | Neratinib | 70.65 | 11.8 | 0.409 | 0.8755 | -0.7838 | -0.9606 | 2.1901 | 0.4163 |
MCF 10A-H2B-mCherry | Taxol | 40.10 | 11.8 | 0.0009 | 0.0013 | -0.7602 | -0.5270 | 2.1898 | 0.9227 |
MCF 10A-H2B-mCherry | Neratinib | 78.53 | 11.8 | Inf | Inf | -0.7553 | -0.9963 | 1.0525 | 0.4438 |
MCF 10A-H2B-mCherry | Neratinib | 64.24 | 12.8 | 0.4495 | 0.6532 | -0.7536 | -0.7620 | 3.3315 | 0.3860 |
MCF 10A-H2B-mCherry | Neratinib | 68.68 | 11.8 | 0.3083 | 0.3924 | -0.7474 | -0.5509 | 4.1022 | 0.4356 |
MCF 10A-H2B-mCherry | Alpelisib | 80.50 | 11.8 | Inf | Inf | -0.7248 | -0.9024 | 0.5606 | 0.5652 |
MCF 10A-H2B-mCherry | Neratinib | 74.59 | 11.8 | Inf | Inf | -0.7181 | -0.9989 | 0.6470 | 0.4952 |