LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
---|---|---|---|---|---|---|---|---|---|
MCF 10A-H2B-mCherry | Alpelisib | 62.27 | 12.8 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | -0.0396 |
MCF 10A-H2B-mCherry | Alpelisib | 60.30 | 12.8 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | -0.0098 |
MCF 10A-H2B-mCherry | Alpelisib | 58.33 | 12.8 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | -0.0079 |
MCF 10A-H2B-mCherry | Alpelisib | 49.95 | 11.8 | Inf | Inf | 0.9252 | 0.9252 | 0.0000 | -0.0030 |
MCF 10A-H2B-mCherry | Alpelisib | 64.24 | 12.8 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | -0.0006 |
MCF 10A-H2B-mCherry | Alpelisib | 56.36 | 12.8 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | 0.0012 |
MCF 10A-H2B-mCherry | Alpelisib | 51.92 | 11.8 | Inf | Inf | 0.9806 | 0.9806 | 0.0000 | 0.0026 |
MCF 10A-H2B-mCherry | Alpelisib | 47.98 | 11.8 | Inf | Inf | 0.8928 | 0.8928 | 0.0000 | 0.0043 |
MCF 10A-H2B-mCherry | Alpelisib | 53.89 | 11.8 | Inf | Inf | 0.9884 | 0.9884 | 0.0000 | 0.0083 |
MCF 10A-H2B-mCherry | Palbociclib | 84.44 | 11.8 | 7.8009 | 9.9225 | -0.0850 | -1.0000 | 5.0000 | 0.0239 |
MCF 10A-H2B-mCherry | Alpelisib | 46.00 | 11.8 | Inf | Inf | 0.8766 | 0.0250 | 0.2295 | 0.0292 |
MCF 10A-H2B-mCherry | Alpelisib | 44.04 | 11.8 | Inf | Inf | 0.8807 | 0.2777 | 0.1810 | 0.0312 |
MCF 10A-H2B-mCherry | Palbociclib | 86.41 | 11.8 | Inf | Inf | 0.2113 | -0.0813 | 2.5000 | 0.0375 |
MCF 10A-H2B-mCherry | Alpelisib | 42.07 | 11.8 | Inf | Inf | 0.7930 | -0.0552 | 0.2023 | 0.0423 |
MCF 10A-H2B-mCherry | Alpelisib | 40.10 | 11.8 | Inf | Inf | 0.7745 | 0.0032 | 0.1903 | 0.0455 |
MCF 10A-H2B-mCherry | Alpelisib | 66.21 | 12.8 | Inf | Inf | 0.7208 | 0.7208 | 0.0000 | 0.0599 |
MCF 10A-H2B-mCherry | Alpelisib | 34.19 | 11.8 | Inf | Inf | 0.6682 | -0.1536 | 0.3663 | 0.0626 |
MCF 10A-H2B-mCherry | Palbociclib | 78.53 | 11.8 | 6.8 | 7.9008 | -0.2637 | -0.6220 | 5.0000 | 0.0666 |
MCF 10A-H2B-mCherry | Palbociclib | 64.24 | 12.8 | Inf | Inf | 0.2311 | 0.2111 | 2.5000 | 0.0711 |
MCF 10A-H2B-mCherry | Palbociclib | 76.56 | 11.8 | 7.1386 | 8.822 | -0.1401 | -0.8206 | 5.0000 | 0.0720 |
MCF 10A-H2B-mCherry | Palbociclib | 80.50 | 11.8 | 6.7725 | 8.2243 | -0.3199 | -0.8211 | 5.0000 | 0.0725 |
MCF 10A-H2B-mCherry | Palbociclib | 66.21 | 12.8 | Inf | Inf | 0.3784 | 0.3627 | 2.5000 | 0.0744 |
MCF 10A-H2B-mCherry | Palbociclib | 82.47 | 11.8 | 5.9596 | 7.8902 | -0.2712 | -0.8072 | 3.8956 | 0.0791 |
MCF 10A-H2B-mCherry | Alpelisib | 38.13 | 11.8 | Inf | Inf | 0.7322 | 0.2688 | 0.1564 | 0.0791 |
MCF 10A-H2B-mCherry | Alpelisib | 32.22 | 11.8 | Inf | Inf | 0.6193 | -0.1765 | 0.3252 | 0.0795 |