LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)

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Cell Small Molecule Time Point (hr) Time Interval (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Alpelisib 62.27 12.8
Inf
Inf
1.0500 1.0500 0.0000 -0.0396
MCF 10A-H2B-mCherry Alpelisib 60.30 12.8
Inf
Inf
1.0500 1.0500 0.0000 -0.0098
MCF 10A-H2B-mCherry Alpelisib 58.33 12.8
Inf
Inf
1.0500 1.0500 0.0000 -0.0079
MCF 10A-H2B-mCherry Alpelisib 49.95 11.8
Inf
Inf
0.9252 0.9252 0.0000 -0.0030
MCF 10A-H2B-mCherry Alpelisib 64.24 12.8
Inf
Inf
1.0500 1.0500 0.0000 -0.0006
MCF 10A-H2B-mCherry Alpelisib 56.36 12.8
Inf
Inf
1.0500 1.0500 0.0000 0.0012
MCF 10A-H2B-mCherry Alpelisib 51.92 11.8
Inf
Inf
0.9806 0.9806 0.0000 0.0026
MCF 10A-H2B-mCherry Alpelisib 47.98 11.8
Inf
Inf
0.8928 0.8928 0.0000 0.0043
MCF 10A-H2B-mCherry Alpelisib 53.89 11.8
Inf
Inf
0.9884 0.9884 0.0000 0.0083
MCF 10A-H2B-mCherry Palbociclib 84.44 11.8
7.8009
9.9225
-0.0850 -1.0000 5.0000 0.0239
MCF 10A-H2B-mCherry Alpelisib 46.00 11.8
Inf
Inf
0.8766 0.0250 0.2295 0.0292
MCF 10A-H2B-mCherry Alpelisib 44.04 11.8
Inf
Inf
0.8807 0.2777 0.1810 0.0312
MCF 10A-H2B-mCherry Palbociclib 86.41 11.8
Inf
Inf
0.2113 -0.0813 2.5000 0.0375
MCF 10A-H2B-mCherry Alpelisib 42.07 11.8
Inf
Inf
0.7930 -0.0552 0.2023 0.0423
MCF 10A-H2B-mCherry Alpelisib 40.10 11.8
Inf
Inf
0.7745 0.0032 0.1903 0.0455
MCF 10A-H2B-mCherry Alpelisib 66.21 12.8
Inf
Inf
0.7208 0.7208 0.0000 0.0599
MCF 10A-H2B-mCherry Alpelisib 34.19 11.8
Inf
Inf
0.6682 -0.1536 0.3663 0.0626
MCF 10A-H2B-mCherry Palbociclib 78.53 11.8
6.8
7.9008
-0.2637 -0.6220 5.0000 0.0666
MCF 10A-H2B-mCherry Palbociclib 64.24 12.8
Inf
Inf
0.2311 0.2111 2.5000 0.0711
MCF 10A-H2B-mCherry Palbociclib 76.56 11.8
7.1386
8.822
-0.1401 -0.8206 5.0000 0.0720
MCF 10A-H2B-mCherry Palbociclib 80.50 11.8
6.7725
8.2243
-0.3199 -0.8211 5.0000 0.0725
MCF 10A-H2B-mCherry Palbociclib 66.21 12.8
Inf
Inf
0.3784 0.3627 2.5000 0.0744
MCF 10A-H2B-mCherry Palbociclib 82.47 11.8
5.9596
7.8902
-0.2712 -0.8072 3.8956 0.0791
MCF 10A-H2B-mCherry Alpelisib 38.13 11.8
Inf
Inf
0.7322 0.2688 0.1564 0.0791
MCF 10A-H2B-mCherry Alpelisib 32.22 11.8
Inf
Inf
0.6193 -0.1765 0.3252 0.0795
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