LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 88.39 | 11.8 | 0.0006 | 0.0007 | -0.5000 | -0.6119 | 5.0000 | 1.1071 |
| MCF 10A-H2B-mCherry | Taxol | 64.24 | 12.8 | 0.0006 | 0.001 | -0.2726 | -0.5948 | 3.1044 | 0.9994 |
| MCF 10A-H2B-mCherry | Taxol | 86.41 | 11.8 | 0.0006 | 0.0007 | -0.5000 | -0.5432 | 4.9994 | 1.0330 |
| MCF 10A-H2B-mCherry | Taxol | 84.44 | 11.8 | 0.0007 | 0.0008 | -0.5000 | -0.4460 | 5.0000 | 0.9331 |
| MCF 10A-H2B-mCherry | Taxol | 51.92 | 11.8 | 0.0007 | 0.0009 | 0.3959 | -0.1137 | 3.3858 | 0.6843 |
| MCF 10A-H2B-mCherry | Taxol | 47.98 | 11.8 | 0.0008 | 0.001 | -0.0628 | -0.3894 | 2.6434 | 0.8589 |
| MCF 10A-H2B-mCherry | Taxol | 49.95 | 11.8 | 0.0008 | 0.001 | 0.1595 | -0.2136 | 3.3339 | 0.7515 |
| MCF 10A-H2B-mCherry | Taxol | 82.47 | 11.8 | 0.0008 | 0.0008 | -0.4992 | -0.3263 | 5.0000 | 0.8223 |
| MCF 10A-H2B-mCherry | Taxol | 46.00 | 11.8 | 0.0008 | 0.0011 | -0.3949 | -0.4741 | 2.3963 | 0.9074 |
| MCF 10A-H2B-mCherry | Taxol | 42.07 | 11.8 | 0.0008 | 0.0012 | -0.4692 | -0.4467 | 2.2248 | 0.8984 |
| MCF 10A-H2B-mCherry | Taxol | 38.13 | 11.8 | 0.0009 | 0.0013 | -0.6497 | -0.5740 | 1.8740 | 0.9604 |
| MCF 10A-H2B-mCherry | Taxol | 80.50 | 11.8 | 0.0009 | 0.0011 | -0.4560 | -0.4969 | 4.9979 | 0.8957 |
| MCF 10A-H2B-mCherry | Taxol | 40.10 | 11.8 | 0.0009 | 0.0013 | -0.7602 | -0.5270 | 2.1898 | 0.9227 |
| MCF 10A-H2B-mCherry | Taxol | 44.04 | 11.8 | 0.0009 | 0.0011 | -0.2097 | -0.3273 | 2.5078 | 0.8390 |
| MCF 10A-H2B-mCherry | Taxol | 36.16 | 11.8 | 0.0009 | 0.0015 | -0.6475 | -0.6132 | 1.7202 | 0.9852 |
| MCF 10A-H2B-mCherry | Taxol | 32.22 | 11.8 | 0.001 | 0.0019 | -0.8341 | -0.7201 | 1.5049 | 0.9893 |
| MCF 10A-H2B-mCherry | Taxol | 34.19 | 11.8 | 0.001 | 0.0016 | -0.6566 | -0.5868 | 1.8654 | 0.9446 |
| MCF 10A-H2B-mCherry | Taxol | 74.59 | 11.8 | 0.0011 | 0.0012 | -0.1346 | -0.2979 | 4.9959 | 0.7808 |
| MCF 10A-H2B-mCherry | Taxol | 76.56 | 11.8 | 0.0011 | 0.0012 | -0.1940 | -0.3600 | 4.9956 | 0.8032 |
| MCF 10A-H2B-mCherry | Taxol | 78.53 | 11.8 | 0.0011 | 0.0012 | -0.4490 | -0.3760 | 4.9969 | 0.8513 |
| MCF 10A-H2B-mCherry | Taxol | 72.62 | 11.8 | 0.0011 | 0.0012 | -0.4139 | -0.4353 | 4.9999 | 0.9083 |
| MCF 10A-H2B-mCherry | Taxol | 30.24 | 11.8 | 0.0011 | 0.0024 | -0.8135 | -0.8348 | 1.2978 | 1.0177 |
| MCF 10A-H2B-mCherry | Taxol | 68.68 | 11.8 | 0.0011 | 0.0012 | -0.3052 | -0.4978 | 4.9979 | 0.9495 |
| MCF 10A-H2B-mCherry | Taxol | 28.28 | 11.8 | 0.0013 | 0.003 | -0.8701 | -0.8390 | 1.2391 | 0.9847 |
| MCF 10A-H2B-mCherry | Taxol | 26.31 | 11.8 | 0.0016 | 0.0039 | -0.9101 | -0.9124 | 1.2276 | 0.9742 |