Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7808.016 | 1.0250 | 1.0221 | 2.2401 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7911.016 | 0.9952 | 0.9928 | 1.3310 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7807.016 | 0.8955 | 0.9000 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7808.016 | 1.0587 | 1.0516 | 2.2401 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7911.016 | 1.0822 | 1.1222 | 1.3310 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7911.016 | 1.0190 | 1.0284 | 1.3310 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7807.016 | 0.9478 | 0.9508 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7807.016 | 0.9831 | 0.9842 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7808.016 | 1.2151 | 1.1817 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7808.016 | 1.0600 | 1.0527 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7808.016 | 0.5467 | 0.5274 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7808.016 | 0.8898 | 0.8985 | 2.2401 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7911.016 | 0.9651 | 0.9473 | 1.3310 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7911.016 | 1.0750 | 1.1117 | 1.3310 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7807.016 | 0.9671 | 0.9691 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7807.016 | 0.9476 | 0.9506 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7807.016 | 0.9697 | 0.9716 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7807.016 | 0.9252 | 0.9290 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7807.016 | 0.0177 | -0.6933 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7807.016 | 0.0055 | -0.8212 | 2.1516 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7808.016 | 0.9843 | 0.9860 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7808.016 | 1.1398 | 1.1203 | 2.2401 | ||
| HBL-100 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7808.016 | 1.1717 | 1.1466 | 2.2401 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7911.016 | 0.0495 | -0.7910 | 1.3310 | ||
| HMT-3522 S1 | Unknown | Unknown | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7911.016 | 0.7317 | 0.5816 | 1.3310 |