Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
184B5
NM
Basal
Nilotinib
ABL
nRTK
1.6
uM
12566.17
0.9380 0.9145 1.4648
600MPE
HR+
Luminal
Nilotinib
ABL
nRTK
0.32
uM
12224.145
1.0747 1.1536 0.9737
184A1
NM
Basal
Nilotinib
ABL
nRTK
8
uM
12509.17
0.9098 0.8689 1.3955
184B5
NM
Basal
Nilotinib
ABL
nRTK
0.32
uM
12566.17
0.9589 0.9436 1.4648
600MPE
HR+
Luminal
Nilotinib
ABL
nRTK
0.000512
uM
12224.145
1.0393 1.0807 0.9737
600MPE
HR+
Luminal
Nilotinib
ABL
nRTK
0.064
uM
12224.145
1.0114 1.0233 0.9737
184A1
NM
Basal
Nilotinib
ABL
nRTK
0.0128
uM
12509.17
0.9642 0.9484 1.3955
184A1
NM
Basal
Nilotinib
ABL
nRTK
1.6
uM
12509.17
0.8925 0.8434 1.3955
184B5
NM
Basal
Nilotinib
ABL
nRTK
0.000512
uM
12566.17
1.0026 1.0035 1.4648
184B5
NM
Basal
Nilotinib
ABL
nRTK
0.064
uM
12566.17
0.9827 0.9763 1.4648
184B5
NM
Basal
Nilotinib
ABL
nRTK
40
uM
12566.17
0.9504 0.9318 1.4648
184B5
NM
Basal
Nilotinib
ABL
nRTK
200
uM
12566.17
0.9436 0.9223 1.4648
600MPE
HR+
Luminal
Nilotinib
ABL
nRTK
0.00256
uM
12224.145
0.9747 0.9481 0.9737
600MPE
HR+
Luminal
Nilotinib
ABL
nRTK
0.0128
uM
12224.145
1.0414 1.0850 0.9737
184A1
NM
Basal
Nilotinib
ABL
nRTK
0.000512
uM
12509.17
1.0051 1.0074 1.3955
184A1
NM
Basal
Nilotinib
ABL
nRTK
0.00256
uM
12509.17
1.0256 1.0365 1.3955
184A1
NM
Basal
Nilotinib
ABL
nRTK
0.064
uM
12509.17
0.9781 0.9686 1.3955
184A1
NM
Basal
Nilotinib
ABL
nRTK
0.32
uM
12509.17
0.9479 0.9248 1.3955
184A1
NM
Basal
Nilotinib
ABL
nRTK
40
uM
12509.17
0.8807 0.8260 1.3955
184A1
NM
Basal
Nilotinib
ABL
nRTK
200
uM
12509.17
0.9381 0.9104 1.3955
184B5
NM
Basal
Nilotinib
ABL
nRTK
0.00256
uM
12566.17
0.9796 0.9720 1.4648
184B5
NM
Basal
Nilotinib
ABL
nRTK
0.0128
uM
12566.17
0.9920 0.9890 1.4648
184B5
NM
Basal
Nilotinib
ABL
nRTK
8
uM
12566.17
0.9553 0.9386 1.4648
600MPE
HR+
Luminal
Nilotinib
ABL
nRTK
8
uM
12224.145
1.0259 1.0533 0.9737
600MPE
HR+
Luminal
Nilotinib
ABL
nRTK
1.6
uM
12224.145
1.0373 1.0766 0.9737
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