Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | AZD8055 | 2 | 72 | 0.0316 | 3917.0 | 7167.9 | 2409.0 | -1.5 | 0.362 | 0.546 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0316 | 4267.0 | 7167.9 | 2409.0 | -1.5 | 0.438 | 0.595 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.1 | 3668.0 | 7167.9 | 2409.0 | -1.0 | 0.306 | 0.512 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.1 | 3681.0 | 7167.9 | 2409.0 | -1.0 | 0.309 | 0.514 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.1 | 3427.0 | 7167.9 | 2409.0 | -1.0 | 0.251 | 0.478 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.1 | 3166.0 | 7167.9 | 2409.0 | -1.0 | 0.190 | 0.442 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.3162 | 3039.0 | 7167.9 | 2409.0 | -0.5 | 0.159 | 0.424 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.3162 | 3078.0 | 7167.9 | 2409.0 | -0.5 | 0.169 | 0.429 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.3162 | 2928.0 | 7167.9 | 2409.0 | -0.5 | 0.132 | 0.408 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.3162 | 2968.0 | 7167.9 | 2409.0 | -0.5 | 0.142 | 0.414 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 3000.0 | 7167.9 | 2409.0 | 0.0 | 0.150 | 0.419 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 2886.0 | 7167.9 | 2409.0 | 0.0 | 0.122 | 0.403 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 2573.0 | 7167.9 | 2409.0 | 0.0 | 0.043 | 0.359 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 2987.0 | 7167.9 | 2409.0 | 0.0 | 0.146 | 0.417 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2838.0 | 7167.9 | 2409.0 | 0.5 | 0.110 | 0.396 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2831.0 | 7167.9 | 2409.0 | 0.5 | 0.108 | 0.395 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2848.0 | 7167.9 | 2409.0 | 0.5 | 0.112 | 0.397 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2590.0 | 7167.9 | 2409.0 | 0.5 | 0.047 | 0.361 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 10.0 | 2466.0 | 7167.9 | 2409.0 | 1.0 | 0.015 | 0.344 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 10.0 | 2129.0 | 7167.9 | 2409.0 | 1.0 | -0.076 | 0.297 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 10.0 | 2344.0 | 7167.9 | 2409.0 | 1.0 | -0.017 | 0.327 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 10.0 | 2141.0 | 7167.9 | 2409.0 | 1.0 | -0.072 | 0.299 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6136.0 | 6533.6 | 1943.1 | -3.0 | 0.929 | 0.939 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6026.0 | 6533.6 | 1943.1 | -3.0 | 0.910 | 0.922 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 0.001 | 6096.0 | 6533.6 | 1943.1 | -3.0 | 0.922 | 0.933 | 1.750 | HCC70 AZD8055 0 3 |