Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 3171.0 | 7580.8 | 2503.8 | 0.0 | 0.159 | 0.418 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 2978.0 | 7580.8 | 2503.8 | 0.0 | 0.115 | 0.393 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 3414.0 | 7580.8 | 2503.8 | 0.0 | 0.214 | 0.450 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3152.0 | 7580.8 | 2503.8 | 0.5 | 0.155 | 0.416 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3106.0 | 7580.8 | 2503.8 | 0.5 | 0.144 | 0.410 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3326.0 | 7580.8 | 2503.8 | 0.5 | 0.194 | 0.439 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3011.0 | 7580.8 | 2503.8 | 0.5 | 0.122 | 0.397 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2787.0 | 7580.8 | 2503.8 | 1.0 | 0.069 | 0.368 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2579.0 | 7580.8 | 2503.8 | 1.0 | 0.019 | 0.340 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2885.0 | 7580.8 | 2503.8 | 1.0 | 0.093 | 0.381 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2785.0 | 7580.8 | 2503.8 | 1.0 | 0.069 | 0.367 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6736.0 | 7167.9 | 2409.0 | -3.0 | 0.923 | 0.940 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6624.0 | 7167.9 | 2409.0 | -3.0 | 0.902 | 0.924 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6048.0 | 7167.9 | 2409.0 | -3.0 | 0.795 | 0.844 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6775.0 | 7167.9 | 2409.0 | -3.0 | 0.930 | 0.945 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0032 | 6432.0 | 7167.9 | 2409.0 | -2.49 | 0.867 | 0.897 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0032 | 6349.0 | 7167.9 | 2409.0 | -2.49 | 0.852 | 0.886 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0032 | 6438.0 | 7167.9 | 2409.0 | -2.49 | 0.868 | 0.898 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0032 | 6454.0 | 7167.9 | 2409.0 | -2.49 | 0.871 | 0.900 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.01 | 5681.0 | 7167.9 | 2409.0 | -2.0 | 0.725 | 0.793 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.01 | 5600.0 | 7167.9 | 2409.0 | -2.0 | 0.710 | 0.781 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.01 | 6054.0 | 7167.9 | 2409.0 | -2.0 | 0.796 | 0.845 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.01 | 5690.0 | 7167.9 | 2409.0 | -2.0 | 0.727 | 0.794 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0316 | 4487.0 | 7167.9 | 2409.0 | -1.5 | 0.485 | 0.626 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0316 | 4658.0 | 7167.9 | 2409.0 | -1.5 | 0.521 | 0.650 | 1.573 | HCC70 AZD8055 0 2 |