Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-IV-100 | 3 | 72 | 0.3162 | 3293.0 | 6533.6 | 1943.1 | -0.5 | 0.352 | 0.504 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.3162 | 2967.0 | 6533.6 | 1943.1 | -0.5 | 0.274 | 0.454 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.3162 | 3143.0 | 6533.6 | 1943.1 | -0.5 | 0.316 | 0.481 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 0.3162 | 3050.0 | 6533.6 | 1943.1 | -0.5 | 0.294 | 0.467 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1205.0 | 6533.6 | 1943.1 | 0.0 | -0.239 | 0.184 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1302.0 | 6533.6 | 1943.1 | 0.0 | -0.205 | 0.199 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1142.0 | 6533.6 | 1943.1 | 0.0 | -0.262 | 0.175 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1027.0 | 6533.6 | 1943.1 | 0.0 | -0.305 | 0.157 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 540.0 | 6533.6 | 1943.1 | 0.5 | -0.519 | 0.083 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 536.0 | 6533.6 | 1943.1 | 0.5 | -0.521 | 0.082 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 544.0 | 6533.6 | 1943.1 | 0.5 | -0.517 | 0.083 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 3.1623 | 582.0 | 6533.6 | 1943.1 | 0.5 | -0.498 | 0.089 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 10.0 | 313.0 | 6533.6 | 1943.1 | 1.0 | -0.648 | 0.048 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 10.0 | 289.0 | 6533.6 | 1943.1 | 1.0 | -0.664 | 0.044 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 10.0 | 299.0 | 6533.6 | 1943.1 | 1.0 | -0.657 | 0.046 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 10.0 | 297.0 | 6533.6 | 1943.1 | 1.0 | -0.658 | 0.046 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-V-107 | 1 | 72 | 0.001 | 7451.0 | 7580.8 | 2503.8 | -3.0 | 0.979 | 0.983 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.001 | 6680.0 | 7580.8 | 2503.8 | -3.0 | 0.848 | 0.881 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.001 | 7243.0 | 7580.8 | 2503.8 | -3.0 | 0.944 | 0.955 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.001 | 7047.0 | 7580.8 | 2503.8 | -3.0 | 0.911 | 0.930 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.0032 | 7166.0 | 7580.8 | 2503.8 | -2.49 | 0.931 | 0.945 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.0032 | 6664.0 | 7580.8 | 2503.8 | -2.49 | 0.845 | 0.879 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.0032 | 6715.0 | 7580.8 | 2503.8 | -2.49 | 0.854 | 0.886 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.0032 | 7048.0 | 7580.8 | 2503.8 | -2.49 | 0.911 | 0.930 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.01 | 7422.0 | 7580.8 | 2503.8 | -2.0 | 0.974 | 0.979 | 1.598 | HCC70 QL-V-107 0 1 |