Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-VI-86 | 1 | 72 | 0.1 | 5889.0 | 7580.8 | 2503.8 | -1.0 | 0.708 | 0.777 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.1 | 6368.0 | 7580.8 | 2503.8 | -1.0 | 0.793 | 0.840 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.3162 | 4170.0 | 7580.8 | 2503.8 | -0.5 | 0.376 | 0.550 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.3162 | 4560.0 | 7580.8 | 2503.8 | -0.5 | 0.455 | 0.602 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.3162 | 4972.0 | 7580.8 | 2503.8 | -0.5 | 0.536 | 0.656 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.3162 | 4909.0 | 7580.8 | 2503.8 | -0.5 | 0.524 | 0.648 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 1.0 | 3207.0 | 7580.8 | 2503.8 | 0.0 | 0.168 | 0.423 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 1.0 | 3111.0 | 7580.8 | 2503.8 | 0.0 | 0.146 | 0.410 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 1.0 | 2952.0 | 7580.8 | 2503.8 | 0.0 | 0.109 | 0.389 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 1.0 | 3431.0 | 7580.8 | 2503.8 | 0.0 | 0.218 | 0.453 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 3.1623 | 1014.0 | 7580.8 | 2503.8 | 0.5 | -0.432 | 0.134 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 3.1623 | 1062.0 | 7580.8 | 2503.8 | 0.5 | -0.415 | 0.140 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 3.1623 | 1011.0 | 7580.8 | 2503.8 | 0.5 | -0.433 | 0.133 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 3.1623 | 1012.0 | 7580.8 | 2503.8 | 0.5 | -0.433 | 0.133 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 10.0 | 434.0 | 7580.8 | 2503.8 | 1.0 | -0.666 | 0.057 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 10.0 | 410.0 | 7580.8 | 2503.8 | 1.0 | -0.678 | 0.054 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 10.0 | 447.0 | 7580.8 | 2503.8 | 1.0 | -0.660 | 0.059 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 10.0 | 382.0 | 7580.8 | 2503.8 | 1.0 | -0.692 | 0.050 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 2 | 72 | 0.001 | 7819.0 | 7167.9 | 2409.0 | -3.0 | 1.110 | 1.090 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 0.001 | 6779.0 | 7167.9 | 2409.0 | -3.0 | 0.930 | 0.946 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 0.001 | 7229.0 | 7167.9 | 2409.0 | -3.0 | 1.010 | 1.010 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 0.001 | 7162.0 | 7167.9 | 2409.0 | -3.0 | 0.999 | 0.999 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 0.0032 | 7411.0 | 7167.9 | 2409.0 | -2.49 | 1.040 | 1.030 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 0.0032 | 7329.0 | 7167.9 | 2409.0 | -2.49 | 1.030 | 1.020 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 0.0032 | 7479.0 | 7167.9 | 2409.0 | -2.49 | 1.050 | 1.040 | 1.573 | HCC70 QL-VI-86 0 2 |