Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-VI-86 | 1 | 72 | 1.0 | 10180.0 | 17793.8 | 2895.7 | 0.0 | 0.616 | 0.572 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 1.0 | 10605.0 | 17793.8 | 2895.7 | 0.0 | 0.641 | 0.596 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 1.0 | 10344.0 | 17793.8 | 2895.7 | 0.0 | 0.626 | 0.581 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 1.0 | 10696.0 | 17793.8 | 2895.7 | 0.0 | 0.647 | 0.601 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 3.1623 | 4268.0 | 17793.8 | 2895.7 | 0.5 | 0.160 | 0.240 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 3.1623 | 4397.0 | 17793.8 | 2895.7 | 0.5 | 0.173 | 0.247 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 3.1623 | 3807.0 | 17793.8 | 2895.7 | 0.5 | 0.110 | 0.214 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 3.1623 | 4005.0 | 17793.8 | 2895.7 | 0.5 | 0.132 | 0.225 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 10.0 | 1541.0 | 17793.8 | 2895.7 | 1.0 | -0.214 | 0.087 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 10.0 | 1527.0 | 17793.8 | 2895.7 | 1.0 | -0.217 | 0.086 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 10.0 | 1659.0 | 17793.8 | 2895.7 | 1.0 | -0.192 | 0.093 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 1 | 72 | 10.0 | 1440.0 | 17793.8 | 2895.7 | 1.0 | -0.234 | 0.081 | 2.619 | HCC1806 QL-VI-86 0 1 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.001 | 13862.0 | 14413.7 | 2222.1 | -3.0 | 0.971 | 0.962 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.001 | 14070.0 | 14413.7 | 2222.1 | -3.0 | 0.982 | 0.976 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.001 | 14432.0 | 14413.7 | 2222.1 | -3.0 | 1.000 | 1.000 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.001 | 14355.0 | 14413.7 | 2222.1 | -3.0 | 0.997 | 0.996 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.0032 | 14361.0 | 14413.7 | 2222.1 | -2.49 | 0.997 | 0.996 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.0032 | 14739.0 | 14413.7 | 2222.1 | -2.49 | 1.020 | 1.020 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.0032 | 13829.0 | 14413.7 | 2222.1 | -2.49 | 0.970 | 0.959 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.0032 | 14372.0 | 14413.7 | 2222.1 | -2.49 | 0.998 | 0.997 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.01 | 14462.0 | 14413.7 | 2222.1 | -2.0 | 1.000 | 1.000 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.01 | 14207.0 | 14413.7 | 2222.1 | -2.0 | 0.989 | 0.986 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.01 | 16947.0 | 14413.7 | 2222.1 | -2.0 | 1.120 | 1.180 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.01 | 14789.0 | 14413.7 | 2222.1 | -2.0 | 1.020 | 1.030 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.0316 | 14710.0 | 14413.7 | 2222.1 | -1.5 | 1.020 | 1.020 | 2.697 | HCC1806 QL-VI-86 0 3 |