Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-IV-100 | 3 | 72 | 1.0 | 1591.0 | 14413.7 | 2222.1 | 0.0 | -0.116 | 0.110 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 1.0 | 1622.0 | 14413.7 | 2222.1 | 0.0 | -0.110 | 0.113 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 3.1623 | 844.0 | 14413.7 | 2222.1 | 0.5 | -0.302 | 0.059 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 3.1623 | 934.0 | 14413.7 | 2222.1 | 0.5 | -0.275 | 0.065 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 3.1623 | 805.0 | 14413.7 | 2222.1 | 0.5 | -0.314 | 0.056 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 3.1623 | 866.0 | 14413.7 | 2222.1 | 0.5 | -0.295 | 0.060 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 10.0 | 736.0 | 14413.7 | 2222.1 | 1.0 | -0.336 | 0.051 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 10.0 | 810.0 | 14413.7 | 2222.1 | 1.0 | -0.312 | 0.056 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 10.0 | 975.0 | 14413.7 | 2222.1 | 1.0 | -0.263 | 0.068 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-IV-100 | 3 | 72 | 10.0 | 871.0 | 14413.7 | 2222.1 | 1.0 | -0.293 | 0.060 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.001 | 17376.0 | 17793.8 | 2895.7 | -3.0 | 0.982 | 0.977 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.001 | 16430.0 | 17793.8 | 2895.7 | -3.0 | 0.940 | 0.923 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.001 | 15643.0 | 17793.8 | 2895.7 | -3.0 | 0.904 | 0.879 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.001 | 17235.0 | 17793.8 | 2895.7 | -3.0 | 0.976 | 0.969 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.0032 | 16843.0 | 17793.8 | 2895.7 | -2.49 | 0.959 | 0.947 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.0032 | 16934.0 | 17793.8 | 2895.7 | -2.49 | 0.963 | 0.952 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.0032 | 16878.0 | 17793.8 | 2895.7 | -2.49 | 0.960 | 0.949 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.0032 | 16747.0 | 17793.8 | 2895.7 | -2.49 | 0.954 | 0.941 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.01 | 18090.0 | 17793.8 | 2895.7 | -2.0 | 1.010 | 1.020 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.01 | 16696.0 | 17793.8 | 2895.7 | -2.0 | 0.952 | 0.938 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.01 | 16853.0 | 17793.8 | 2895.7 | -2.0 | 0.959 | 0.947 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.01 | 17939.0 | 17793.8 | 2895.7 | -2.0 | 1.010 | 1.010 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.0316 | 16294.0 | 17793.8 | 2895.7 | -1.5 | 0.934 | 0.916 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.0316 | 16000.0 | 17793.8 | 2895.7 | -1.5 | 0.920 | 0.899 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 0.0316 | 16597.0 | 17793.8 | 2895.7 | -1.5 | 0.948 | 0.933 | 2.619 | HCC1806 QL-V-107 0 1 |